High-Resolution Genomic Profiling of Chromosomal Abnormalities in Human Stem Cells Using the 135 K StemArray
Culturing stem cells for an extended period of time can lead to acquired chromosomal aberrations. Determining the copy number variant (CNV) profile of stem cell lines is critical since CNVs can have dramatic effects on gene expression and tumorigenic potential. Here, we describe an improved version...
Main Authors: | Aaron M. Elliott, Kristi A. Hohenstein Elliott, Anja Kammesheidt |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2012-01-01
|
Series: | Stem Cells International |
Online Access: | http://dx.doi.org/10.1155/2012/431534 |
Similar Items
-
Isolation and genomic analysis of the Cetacean Y-chromosome
by: Elliott, Vittoria Louise
Published: (2010) -
Studying Abnormal Chromosomal Diseases Using Patient-Derived Induced Pluripotent Stem Cells
by: Yohei Hayashi, et al.
Published: (2020-08-01) -
Genomic imprinting and the aetiology of human chromosome abnormalities
by: James, Rowena Sarah
Published: (1995) -
A Glutamine-Rich Factor Affects Stem Cell Genesis in Leech
by: Kristi A. Hohenstein, et al.
Published: (2010-01-01) -
Telomere resolution and genomic instability in mouse embryonic stem cells
by: Lisaingo, Kathleen
Published: (2012)