Evaluation of Masood’s and Modified Masood’s Scoring Systems in the Cytological Diagnosis of Palpable Breast Lump Aspirates
Introduction: Fine Needle Aspiration Cytology (FNAC) has a leading role in the assessment of breast lesions. Masood’s Scoring Index (MSI) and its modification (Modified Masood’s scoring index; MMSI) has been proposed to aid in sub-grouping breast lesions and to help in subsequent management. Ai...
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doaj-b27d4820c5814744ae526a0cb56cba8f2020-11-25T02:19:33ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-04-01114EC06EC1010.7860/JCDR/2017/22817.9558Evaluation of Masood’s and Modified Masood’s Scoring Systems in the Cytological Diagnosis of Palpable Breast Lump AspiratesSmrithi Krishna Cherath0Savithri Moothiringode Chithrabhanu1Consultant Pathologist, Department of Pathology, Moulana Hospital, Perinthalmanna, Kerala, India.Associate Professor, Department of Pathology, Amala Institute of Medical Sciences, Amala Nagar, Thrissur, Kerala.Introduction: Fine Needle Aspiration Cytology (FNAC) has a leading role in the assessment of breast lesions. Masood’s Scoring Index (MSI) and its modification (Modified Masood’s scoring index; MMSI) has been proposed to aid in sub-grouping breast lesions and to help in subsequent management. Aim: To assess and compare the diagnostic accuracy of MSI and MMSI by subsequent correlation with histopathology. Materials and Methods: The study was cross-sectional in nature and was conducted in a tertiary care setting. The study included 207 cases presenting as palpable breast lump, which had undergone FNAC and subsequent excision biopsy for histopathology. Statistical Analysis: The cases were grouped into four categories as suggested by Masood et al., (MSI) and Nandini et al., (MMSI) and concordance analysis with reference to histopathological diagnosis was done. Results: In comparison to MSI, MMSI showed better concordance with histopathological diagnosis and superior diagnostic accuracy in non-proliferative breast disease category (p-value = 0.046) as well as in proliferative breast disease without atypia category. The overall diagnostic accuracy of the cytological scoring was 97.5%, with 94.5% sensitivity and 100% specificity. Conclusion: Though both MSI and MMSI were found effective in subcategorizing breast lesions, MMSI was found to have better concordance with histopathology. Inclusion of cellular pattern and background material may further help in increasing the accuracy.https://jcdr.net/articles/PDF/9558/22817_CE(RA1)_F(T)_PF1(ShGH)_PFA(P)_PF2(P_SH).pdfbreast carcinomafine needle aspiration cytology of breastnon-proliferative breast diseaseproliferative breast disease |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Smrithi Krishna Cherath Savithri Moothiringode Chithrabhanu |
spellingShingle |
Smrithi Krishna Cherath Savithri Moothiringode Chithrabhanu Evaluation of Masood’s and Modified Masood’s Scoring Systems in the Cytological Diagnosis of Palpable Breast Lump Aspirates Journal of Clinical and Diagnostic Research breast carcinoma fine needle aspiration cytology of breast non-proliferative breast disease proliferative breast disease |
author_facet |
Smrithi Krishna Cherath Savithri Moothiringode Chithrabhanu |
author_sort |
Smrithi Krishna Cherath |
title |
Evaluation of Masood’s and Modified Masood’s Scoring Systems in the Cytological Diagnosis of Palpable Breast Lump Aspirates |
title_short |
Evaluation of Masood’s and Modified Masood’s Scoring Systems in the Cytological Diagnosis of Palpable Breast Lump Aspirates |
title_full |
Evaluation of Masood’s and Modified Masood’s Scoring Systems in the Cytological Diagnosis of Palpable Breast Lump Aspirates |
title_fullStr |
Evaluation of Masood’s and Modified Masood’s Scoring Systems in the Cytological Diagnosis of Palpable Breast Lump Aspirates |
title_full_unstemmed |
Evaluation of Masood’s and Modified Masood’s Scoring Systems in the Cytological Diagnosis of Palpable Breast Lump Aspirates |
title_sort |
evaluation of masood’s and modified masood’s scoring systems in the cytological diagnosis of palpable breast lump aspirates |
publisher |
JCDR Research and Publications Private Limited |
series |
Journal of Clinical and Diagnostic Research |
issn |
2249-782X 0973-709X |
publishDate |
2017-04-01 |
description |
Introduction: Fine Needle Aspiration Cytology (FNAC) has
a leading role in the assessment of breast lesions. Masood’s
Scoring Index (MSI) and its modification (Modified Masood’s
scoring index; MMSI) has been proposed to aid in sub-grouping
breast lesions and to help in subsequent management.
Aim: To assess and compare the diagnostic accuracy of MSI
and MMSI by subsequent correlation with histopathology.
Materials and Methods: The study was cross-sectional in
nature and was conducted in a tertiary care setting. The study
included 207 cases presenting as palpable breast lump, which
had undergone FNAC and subsequent excision biopsy for
histopathology.
Statistical Analysis: The cases were grouped into four categories
as suggested by Masood et al., (MSI) and Nandini et al., (MMSI)
and concordance analysis with reference to histopathological
diagnosis was done.
Results: In comparison to MSI, MMSI showed better concordance with histopathological diagnosis and superior diagnostic
accuracy in non-proliferative breast disease category (p-value =
0.046) as well as in proliferative breast disease without atypia
category. The overall diagnostic accuracy of the cytological
scoring was 97.5%, with 94.5% sensitivity and 100% specificity.
Conclusion: Though both MSI and MMSI were found effective
in subcategorizing breast lesions, MMSI was found to have
better concordance with histopathology. Inclusion of cellular
pattern and background material may further help in increasing
the accuracy. |
topic |
breast carcinoma fine needle aspiration cytology of breast non-proliferative breast disease proliferative breast disease |
url |
https://jcdr.net/articles/PDF/9558/22817_CE(RA1)_F(T)_PF1(ShGH)_PFA(P)_PF2(P_SH).pdf |
work_keys_str_mv |
AT smrithikrishnacherath evaluationofmasoodsandmodifiedmasoodsscoringsystemsinthecytologicaldiagnosisofpalpablebreastlumpaspirates AT savithrimoothiringodechithrabhanu evaluationofmasoodsandmodifiedmasoodsscoringsystemsinthecytologicaldiagnosisofpalpablebreastlumpaspirates |
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