The Lymphotoxin β Receptor Is Essential for Upregulation of IFN-Induced Guanylate-Binding Proteins and Survival after Toxoplasma gondii Infection
Lymphotoxin β receptor (LTβR) signaling plays an important role in efficient initiation of host responses to a variety of pathogens, encompassing viruses, bacteria, and protozoans via induction of the type I interferon response. The present study reveals that after Toxoplasma gondii infection, LTβR−...
Main Authors: | Kristina Behnke, Ursula R. Sorg, Helmut E. Gabbert, Klaus Pfeffer |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2017-01-01
|
Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2017/7375818 |
Similar Items
-
Guanylate binding proteins directly attack Toxoplasma gondii via supramolecular complexes
by: Elisabeth Kravets, et al.
Published: (2016-01-01) -
Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii.
by: Elizabeth M Selleck, et al.
Published: (2013-01-01) -
Human guanylate binding proteins : generation of tools, and their role during Toxoplasma gondii infection
by: Johnston, A. C.
Published: (2017) -
NADPH Oxidase and Guanylate Binding Protein 5 Restrict Survival of Avirulent Type III Strains of Toxoplasma gondii in Naive Macrophages
by: Sumit K. Matta, et al.
Published: (2018-08-01) -
Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection
by: Nora Steffens, et al.
Published: (2020-01-01)