An epistatic explanation
Interactions between two gene variants that rarely cause midline craniosynostosis on their own make the development of the disorder a certainty.
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| Format: | Article |
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eLife Sciences Publications Ltd
2016-09-01
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| Series: | eLife |
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| Online Access: | https://elifesciences.org/articles/21162 |
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doaj-b29e0c8f394249cface19c2e07ff135c2021-05-05T00:36:53ZengeLife Sciences Publications LtdeLife2050-084X2016-09-01510.7554/eLife.21162An epistatic explanationYoshihiro Komatsu0Yuji Mishina1Department of Pediatrics, The University of Texas Medical School at Houston, Houston, United StatesDepartment of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, United StatesInteractions between two gene variants that rarely cause midline craniosynostosis on their own make the development of the disorder a certainty.https://elifesciences.org/articles/21162craniosynostosiscraniofacialexome sequencinghuman geneticsde novo mutationincomplete penetrance |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Yoshihiro Komatsu Yuji Mishina |
| spellingShingle |
Yoshihiro Komatsu Yuji Mishina An epistatic explanation eLife craniosynostosis craniofacial exome sequencing human genetics de novo mutation incomplete penetrance |
| author_facet |
Yoshihiro Komatsu Yuji Mishina |
| author_sort |
Yoshihiro Komatsu |
| title |
An epistatic explanation |
| title_short |
An epistatic explanation |
| title_full |
An epistatic explanation |
| title_fullStr |
An epistatic explanation |
| title_full_unstemmed |
An epistatic explanation |
| title_sort |
epistatic explanation |
| publisher |
eLife Sciences Publications Ltd |
| series |
eLife |
| issn |
2050-084X |
| publishDate |
2016-09-01 |
| description |
Interactions between two gene variants that rarely cause midline craniosynostosis on their own make the development of the disorder a certainty. |
| topic |
craniosynostosis craniofacial exome sequencing human genetics de novo mutation incomplete penetrance |
| url |
https://elifesciences.org/articles/21162 |
| work_keys_str_mv |
AT yoshihirokomatsu anepistaticexplanation AT yujimishina anepistaticexplanation AT yoshihirokomatsu epistaticexplanation AT yujimishina epistaticexplanation |
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