Biochemical and Cytological Comparison of Keratocystic Odontogenic Tumours to Nonkeratinising Odontogenic Cysts Fluid
Aim: To evaluate the levels of albumin, prealbumin, total protein, inorganic phosphate and presence of keratinocytes in the cystic fluid for the diagnosis and appropriate treatment planning of keratocystic odontogenic tumours and other non keratinizing odontogenic cysts. Materials and Methods:...
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doaj-b2a12a264e3044b4b29e4c4b51d32a222020-11-25T03:59:50ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-07-0197ZC34ZC3810.7860/JCDR/2015/12501.6195Biochemical and Cytological Comparison of Keratocystic Odontogenic Tumours to Nonkeratinising Odontogenic Cysts FluidMadhvika Patidar0Pushparaj Shetty1Nitesh Patidar2Sugandh Mittal3Hanspal Singh4Chethna5Senior Lecturer, Department of Oral Pathology and Microbiology, Babu Banarasi Das College of Dental Sciences, Lucknow, India.Professor and HOD, Department of Oral Pathology and Microbiology, A B Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India.Senior Resident, Department of Urology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.Private Practitioner, COPE healthcare, Bangalore, Karnataka, India.Senior Resident, Department of Oral Pathology and Microbiology, Maulana Azad Institute of Dental Sciences, New Delhi, India.Senior Lecturer, Department of Oral Pathology and Microbiology, A B Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India.Aim: To evaluate the levels of albumin, prealbumin, total protein, inorganic phosphate and presence of keratinocytes in the cystic fluid for the diagnosis and appropriate treatment planning of keratocystic odontogenic tumours and other non keratinizing odontogenic cysts. Materials and Methods: Fifteen keratocystic odontogenic tumour and 15 controls were studied. The cystic fluid was aspirated and analysed to determine the levels of albumin, prealbumin, total protein, inorganic phosphate and the presence of keratinocytes. The data collected was statistically evaluated using Mann Whitney U-Test and Student’s t-test. Results: A highly significant difference (p<0.0001) was seen when a comparison of Prealbumin, total protein, inorganic phosphate and presence of keratinocytes was made between keratocystic odontogenic tumour and non keratinizing odontogenic cysts. The presence of albumin also showed a significant difference (p<0.01). Conclusion: A combined analysis of total protein, albumin, prealbumin, inorganic phosphorous and detection of epithelial squames may be used as a diagnostic adjunct in the preoperative diagnosis of keratocystic odontogenic tumour in a minimally invasive and highly accurate fashion.https://jcdr.net/articles/PDF/6195/12501_CE[Ra1]_F(AK)_PF1(PAK)_PFA(AK)_PF2(PAG).pdfcyst fluidsdentigerous cystodontogenic keratocystradicular cyst |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Madhvika Patidar Pushparaj Shetty Nitesh Patidar Sugandh Mittal Hanspal Singh Chethna |
spellingShingle |
Madhvika Patidar Pushparaj Shetty Nitesh Patidar Sugandh Mittal Hanspal Singh Chethna Biochemical and Cytological Comparison of Keratocystic Odontogenic Tumours to Nonkeratinising Odontogenic Cysts Fluid Journal of Clinical and Diagnostic Research cyst fluids dentigerous cyst odontogenic keratocyst radicular cyst |
author_facet |
Madhvika Patidar Pushparaj Shetty Nitesh Patidar Sugandh Mittal Hanspal Singh Chethna |
author_sort |
Madhvika Patidar |
title |
Biochemical and Cytological Comparison of Keratocystic Odontogenic Tumours to Nonkeratinising Odontogenic Cysts Fluid |
title_short |
Biochemical and Cytological Comparison of Keratocystic Odontogenic Tumours to Nonkeratinising Odontogenic Cysts Fluid |
title_full |
Biochemical and Cytological Comparison of Keratocystic Odontogenic Tumours to Nonkeratinising Odontogenic Cysts Fluid |
title_fullStr |
Biochemical and Cytological Comparison of Keratocystic Odontogenic Tumours to Nonkeratinising Odontogenic Cysts Fluid |
title_full_unstemmed |
Biochemical and Cytological Comparison of Keratocystic Odontogenic Tumours to Nonkeratinising Odontogenic Cysts Fluid |
title_sort |
biochemical and cytological comparison of keratocystic odontogenic tumours to nonkeratinising odontogenic cysts fluid |
publisher |
JCDR Research and Publications Private Limited |
series |
Journal of Clinical and Diagnostic Research |
issn |
2249-782X 0973-709X |
publishDate |
2015-07-01 |
description |
Aim: To evaluate the levels of albumin, prealbumin, total protein,
inorganic phosphate and presence of keratinocytes in the cystic
fluid for the diagnosis and appropriate treatment planning of
keratocystic odontogenic tumours and other non keratinizing
odontogenic cysts.
Materials and Methods: Fifteen keratocystic odontogenic
tumour and 15 controls were studied. The cystic fluid was
aspirated and analysed to determine the levels of albumin,
prealbumin, total protein, inorganic phosphate and the presence
of keratinocytes. The data collected was statistically evaluated
using Mann Whitney U-Test and Student’s t-test.
Results: A highly significant difference (p<0.0001) was seen when
a comparison of Prealbumin, total protein, inorganic phosphate
and presence of keratinocytes was made between keratocystic
odontogenic tumour and non keratinizing odontogenic cysts.
The presence of albumin also showed a significant difference
(p<0.01).
Conclusion: A combined analysis of total protein, albumin,
prealbumin, inorganic phosphorous and detection of epithelial
squames may be used as a diagnostic adjunct in the preoperative
diagnosis of keratocystic odontogenic tumour in a minimally
invasive and highly accurate fashion. |
topic |
cyst fluids dentigerous cyst odontogenic keratocyst radicular cyst |
url |
https://jcdr.net/articles/PDF/6195/12501_CE[Ra1]_F(AK)_PF1(PAK)_PFA(AK)_PF2(PAG).pdf |
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