A Bayesian network analysis of posttraumatic stress disorder symptoms in adults reporting childhood sexual abuse

Background: The network approach to mental disorders offers a novel framework for conceptualizing posttraumatic stress disorder (PTSD) as a causal system of interacting symptoms. Objective: In this study, we extended this work by estimating the structure of relations among PTSD symptoms in adults re...

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Main Authors: Richard J. McNally, Alexandre Heeren, Donald J. Robinaugh
Format: Article
Language:English
Published: Taylor & Francis Group 2017-11-01
Series:European Journal of Psychotraumatology
Subjects:
Online Access:http://dx.doi.org/10.1080/20008198.2017.1341276
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spelling doaj-b2b3936cfbd142f8a251f4f832b382a02020-11-25T01:25:29ZengTaylor & Francis GroupEuropean Journal of Psychotraumatology2000-81982000-80662017-11-018010.1080/20008198.2017.13412761341276A Bayesian network analysis of posttraumatic stress disorder symptoms in adults reporting childhood sexual abuseRichard J. McNally0Alexandre Heeren1Donald J. Robinaugh2Harvard UniversityHarvard UniversityMassachusetts General Hospital and Harvard Medical SchoolBackground: The network approach to mental disorders offers a novel framework for conceptualizing posttraumatic stress disorder (PTSD) as a causal system of interacting symptoms. Objective: In this study, we extended this work by estimating the structure of relations among PTSD symptoms in adults reporting personal histories of childhood sexual abuse (CSA; N = 179).   Method: We employed two complementary methods. First, using the graphical LASSO, we computed a sparse, regularized partial correlation network revealing associations (edges) between pairs of PTSD symptoms (nodes). Next, using a Bayesian approach, we computed a directed acyclic graph (DAG) to estimate a directed, potentially causal model of the relations among symptoms. Results: For the first network, we found that physiological reactivity to reminders of trauma, dreams about the trauma, and lost of interest in previously enjoyed activities were highly central nodes. However, stability analyses suggest that these findings were unstable across subsets of our sample. The DAG suggests that becoming physiologically reactive and upset in response to reminders of the trauma may be key drivers of other symptoms in adult survivors of CSA. Conclusions: Our study illustrates the strengths and limitations of these network analytic approaches to PTSD.http://dx.doi.org/10.1080/20008198.2017.1341276Network analysisdirected acyclic graphPTSDchildhood sexual abuse
collection DOAJ
language English
format Article
sources DOAJ
author Richard J. McNally
Alexandre Heeren
Donald J. Robinaugh
spellingShingle Richard J. McNally
Alexandre Heeren
Donald J. Robinaugh
A Bayesian network analysis of posttraumatic stress disorder symptoms in adults reporting childhood sexual abuse
European Journal of Psychotraumatology
Network analysis
directed acyclic graph
PTSD
childhood sexual abuse
author_facet Richard J. McNally
Alexandre Heeren
Donald J. Robinaugh
author_sort Richard J. McNally
title A Bayesian network analysis of posttraumatic stress disorder symptoms in adults reporting childhood sexual abuse
title_short A Bayesian network analysis of posttraumatic stress disorder symptoms in adults reporting childhood sexual abuse
title_full A Bayesian network analysis of posttraumatic stress disorder symptoms in adults reporting childhood sexual abuse
title_fullStr A Bayesian network analysis of posttraumatic stress disorder symptoms in adults reporting childhood sexual abuse
title_full_unstemmed A Bayesian network analysis of posttraumatic stress disorder symptoms in adults reporting childhood sexual abuse
title_sort bayesian network analysis of posttraumatic stress disorder symptoms in adults reporting childhood sexual abuse
publisher Taylor & Francis Group
series European Journal of Psychotraumatology
issn 2000-8198
2000-8066
publishDate 2017-11-01
description Background: The network approach to mental disorders offers a novel framework for conceptualizing posttraumatic stress disorder (PTSD) as a causal system of interacting symptoms. Objective: In this study, we extended this work by estimating the structure of relations among PTSD symptoms in adults reporting personal histories of childhood sexual abuse (CSA; N = 179).   Method: We employed two complementary methods. First, using the graphical LASSO, we computed a sparse, regularized partial correlation network revealing associations (edges) between pairs of PTSD symptoms (nodes). Next, using a Bayesian approach, we computed a directed acyclic graph (DAG) to estimate a directed, potentially causal model of the relations among symptoms. Results: For the first network, we found that physiological reactivity to reminders of trauma, dreams about the trauma, and lost of interest in previously enjoyed activities were highly central nodes. However, stability analyses suggest that these findings were unstable across subsets of our sample. The DAG suggests that becoming physiologically reactive and upset in response to reminders of the trauma may be key drivers of other symptoms in adult survivors of CSA. Conclusions: Our study illustrates the strengths and limitations of these network analytic approaches to PTSD.
topic Network analysis
directed acyclic graph
PTSD
childhood sexual abuse
url http://dx.doi.org/10.1080/20008198.2017.1341276
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