From Recoding to Peptides for MHC Class I Immune Display: Enriching Viral Expression, Virus Vulnerability and Virus Evasion

From Recoding to Peptides for MHC Class I Immune Display: Enriching Viral Expression, Virus Vulnerability and Virus Evasion

Many viruses, especially RNA viruses, utilize programmed ribosomal frameshifting and/or stop codon readthrough in their expression, and in the decoding of a few a UGA is dynamically redefined to specify selenocysteine. This recoding can effectively increase viral coding capacity and generate a set r...

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Bibliographic Details
Main Authors: John F. Atkins, Kate M. O’Connor, Pramod R. Bhatt, Gary Loughran
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Viruses
Subjects:
StopGo
ribosomal frameshifting
stop codon readthrough
codon redefinition
selenocysteine
bet hedging
Online Access:https://www.mdpi.com/1999-4915/13/7/1251

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