Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence

• Main Authors: Wenjing Ye, Wen Gu, Xuejun Guo, Ping Yi, Yishuang Meng, Fengfeng Han, Lingwei Yu, Yi Chen, Guorui Zhang, Xueting Wang
• Format: Article
• Language: English
• Published: BMC 2019-01-01
• Series: BioMedical Engineering OnLine
• Subjects: Pulmonary nodule; Ground-glass opacity; Deep learning; Artificial intelligence; Computer-aided diagnosis
• Online Access: http://link.springer.com/article/10.1186/s12938-019-0627-4

Abstract Background A deep learning computer artificial intelligence system is helpful for early identification of ground glass opacities (GGOs). Methods Images from the Lung Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI) database were used in AlexNet and GoogLeNet to detect pulmonary nodules, and 221 GGO images provided by Xinhua Hospital were used in ResNet50 for detecting GGOs. We used computed tomography image radial reorganization to create the input image of the three-dimensional features, and used the extracted features for deep learning, network training, testing, and analysis. Results In the final evaluation results, we found that the accuracy of identification of lung nodule could reach 88.0%, with an F-score of 0.891. In terms of performance and accuracy, our method was better than the existing solutions. The GGO nodule classification achieved the best F-score of 0.87805. We propose a preprocessing method of red, green, and blue (RGB) superposition in the region of interest to effectively increase the differentiation between nodules and normal tissues, and that is the innovation of our research. Conclusions The method of deep learning proposed in this study is more sensitive than other systems in recent years, and the average false positive is lower than that of others.