Cytotoxic and inflammatory potential of a phospholipase A2 from Bothrops jararaca snake venom

Cytotoxic and inflammatory potential of a phospholipase A2 from Bothrops jararaca snake venom

Abstract Background Snake venom phospholipases A2 (PLA2s) have been reported to induce myotoxic, neurotoxic, hemolytic, edematogenic, cytotoxic and proinflammatory effects. This work aimed at the isolation and functional characterization of a PLA2 isolated from Bothrops jararaca venom, named BJ-PLA2...

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Main Authors: Rafhaella C. A. Cedro, Danilo L. Menaldo, Tássia R. Costa, Karina F. Zoccal, Marco A. Sartim, Norival A. Santos-Filho, Lúcia H. Faccioli, Suely V. Sampaio
Format: Article
Language:English
Published: SciELO 2018-11-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
Snake venom
Bothrops jararaca
Phospholipase A2
Inflammation
Cytotoxicity
Online Access:http://link.springer.com/article/10.1186/s40409-018-0170-y

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