Surveillance of respiratory syncytial virus infections in adults, Austria, 2017 to 2019

Abstract Respiratory syncytial virus (RSV) testing is generally available in most care centres, but it is rarely performed because clinicians’ seldom suspect RSV to be the underlying pathogen in adults with respiratory disease. Here, we evaluate the impact of broad combined influenza/RSV testing on...

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Main Authors: Lorenz Schubert, Johanna Steininger, Felix Lötsch, Anna Nele Herdina, Monika Redlberger-Fritz, Selma Tobudic, Michael Kundi, Robert Strassl, Christoph Steininger
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88537-5
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spelling doaj-b2c5b4207d89491a93f3ff02c45de4522021-05-02T11:36:35ZengNature Publishing GroupScientific Reports2045-23222021-04-011111710.1038/s41598-021-88537-5Surveillance of respiratory syncytial virus infections in adults, Austria, 2017 to 2019Lorenz Schubert0Johanna Steininger1Felix Lötsch2Anna Nele Herdina3Monika Redlberger-Fritz4Selma Tobudic5Michael Kundi6Robert Strassl7Christoph Steininger8Division of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University of ViennaDivision of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University of ViennaDivision of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University of ViennaDivision of Clinical Virology, Department of Laboratory Medicine, Medical University of ViennaDepartment of Virology, Medical University ViennaDivision of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University of ViennaDepartment for Environmental Health, Center for Public Health, Medical University of ViennaDivision of Clinical Virology, Department of Laboratory Medicine, Medical University of ViennaDivision of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University of ViennaAbstract Respiratory syncytial virus (RSV) testing is generally available in most care centres, but it is rarely performed because clinicians’ seldom suspect RSV to be the underlying pathogen in adults with respiratory disease. Here, we evaluate the impact of broad combined influenza/RSV testing on the clinical practice. Overall, 103 patients were tested positively for RSV. Our study indicates that positively tested patients were mostly of advanced age and suffered from chronic diseases. Mortality was significant in our cohort and higher in patients with advanced age. Further, we report a significant increase in detected RSV cases but also in detection rate. Together, these findings suggest that implementation of a combined influenza/RSV testing led to a significant increase in detection rate, supported clinicians establishing the correct diagnosis and allowed a safe and controlled handling of RSV patients.https://doi.org/10.1038/s41598-021-88537-5
collection DOAJ
language English
format Article
sources DOAJ
author Lorenz Schubert
Johanna Steininger
Felix Lötsch
Anna Nele Herdina
Monika Redlberger-Fritz
Selma Tobudic
Michael Kundi
Robert Strassl
Christoph Steininger
spellingShingle Lorenz Schubert
Johanna Steininger
Felix Lötsch
Anna Nele Herdina
Monika Redlberger-Fritz
Selma Tobudic
Michael Kundi
Robert Strassl
Christoph Steininger
Surveillance of respiratory syncytial virus infections in adults, Austria, 2017 to 2019
Scientific Reports
author_facet Lorenz Schubert
Johanna Steininger
Felix Lötsch
Anna Nele Herdina
Monika Redlberger-Fritz
Selma Tobudic
Michael Kundi
Robert Strassl
Christoph Steininger
author_sort Lorenz Schubert
title Surveillance of respiratory syncytial virus infections in adults, Austria, 2017 to 2019
title_short Surveillance of respiratory syncytial virus infections in adults, Austria, 2017 to 2019
title_full Surveillance of respiratory syncytial virus infections in adults, Austria, 2017 to 2019
title_fullStr Surveillance of respiratory syncytial virus infections in adults, Austria, 2017 to 2019
title_full_unstemmed Surveillance of respiratory syncytial virus infections in adults, Austria, 2017 to 2019
title_sort surveillance of respiratory syncytial virus infections in adults, austria, 2017 to 2019
publisher Nature Publishing Group
series Scientific Reports
issn 2045-2322
publishDate 2021-04-01
description Abstract Respiratory syncytial virus (RSV) testing is generally available in most care centres, but it is rarely performed because clinicians’ seldom suspect RSV to be the underlying pathogen in adults with respiratory disease. Here, we evaluate the impact of broad combined influenza/RSV testing on the clinical practice. Overall, 103 patients were tested positively for RSV. Our study indicates that positively tested patients were mostly of advanced age and suffered from chronic diseases. Mortality was significant in our cohort and higher in patients with advanced age. Further, we report a significant increase in detected RSV cases but also in detection rate. Together, these findings suggest that implementation of a combined influenza/RSV testing led to a significant increase in detection rate, supported clinicians establishing the correct diagnosis and allowed a safe and controlled handling of RSV patients.
url https://doi.org/10.1038/s41598-021-88537-5
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