CD73 facilitates EMT progression and promotes lung metastases in triple-negative breast cancer

CD73 facilitates EMT progression and promotes lung metastases in triple-negative breast cancer

Abstract CD73 is a cell surface ecto-5′-nucleotidase, which converts extracellular adenosine monophosphate to adenosine. High tumor CD73 expression is associated with poor outcome among triple-negative breast cancer (TNBC) patients. Here we investigated the mechanisms by which CD73 might contribute...

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Bibliographic Details
Main Authors: Nataliia Petruk, Sanni Tuominen, Malin Åkerfelt, Jesse Mattsson, Jouko Sandholm, Matthias Nees, Gennady G. Yegutkin, Arja Jukkola, Johanna Tuomela, Katri S. Selander
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85379-z

Internet

https://doi.org/10.1038/s41598-021-85379-z

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