MicroRNA-200b and microRNA-200c are up-regulated in PCOS granulosa cell and inhibit KGN cell proliferation via targeting PTEN

MicroRNA-200b and microRNA-200c are up-regulated in PCOS granulosa cell and inhibit KGN cell proliferation via targeting PTEN

Abstract Background Polycystic ovary syndrome (PCOS) is one of the most common endocrine metabolic disorders characterized by hyperandrogenism, polycystic ovaries and ovulatory dysfunction. Several studies have reported that the aberrant expression of miRNAs contributes a lot to disordered folliculo...

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Bibliographic Details
Main Authors: Tingting He, Yifei Sun, Yingchun Zhang, Shigang Zhao, Yanjun Zheng, Guimin Hao, Yuhua Shi
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Reproductive Biology and Endocrinology
Subjects:
Polycystic ovary syndrome
microRNA-200b
microRNA-200c
Proliferation
PTEN
Online Access:http://link.springer.com/article/10.1186/s12958-019-0505-8

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