Detection and characterization of two chimpanzee polyomavirus genotypes from different subspecies

Detection and characterization of two chimpanzee polyomavirus genotypes from different subspecies

<p>Abstract</p> <p>The complete nucleotide sequences of three chimpanzee polyomavirus genetic variants were determined. Phylogenetic analysis indicated that the viruses form two different genotypes of ChPyV. Comparison with other primate polyomaviruses revealed a putative agnogene,...

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Main Authors: Niphuis Henk, Groenewoud Marlous J, Fagrouch Zahra, Deuzing Ilona, Kondova Ivanela, Bogers Willy, Verschoor Ernst J
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/7/1/347
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spelling doaj-b2ecf45305454f48a057c6700321fdcd2020-11-25T00:23:57ZengBMCVirology Journal1743-422X2010-11-017134710.1186/1743-422X-7-347Detection and characterization of two chimpanzee polyomavirus genotypes from different subspeciesNiphuis HenkGroenewoud Marlous JFagrouch ZahraDeuzing IlonaKondova IvanelaBogers WillyVerschoor Ernst J<p>Abstract</p> <p>The complete nucleotide sequences of three chimpanzee polyomavirus genetic variants were determined. Phylogenetic analysis indicated that the viruses form two different genotypes of ChPyV. Comparison with other primate polyomaviruses revealed a putative agnogene, and an unusually long VP1 open reading frame. The transcriptional control regions (TCR) of the viruses were extremely short (155 nucleotides), and highly conserved amongst the genotypes. Analysis of the TCR from different chimpanzee subspecies, and from a series of tissues from five individuals confirmed its genetic stability, and also indicates that double-infections with different genotypes can occur.</p> http://www.virologyj.com/content/7/1/347
collection DOAJ
language English
format Article
sources DOAJ
author Niphuis Henk
Groenewoud Marlous J
Fagrouch Zahra
Deuzing Ilona
Kondova Ivanela
Bogers Willy
Verschoor Ernst J
spellingShingle Niphuis Henk
Groenewoud Marlous J
Fagrouch Zahra
Deuzing Ilona
Kondova Ivanela
Bogers Willy
Verschoor Ernst J
Detection and characterization of two chimpanzee polyomavirus genotypes from different subspecies
Virology Journal
author_facet Niphuis Henk
Groenewoud Marlous J
Fagrouch Zahra
Deuzing Ilona
Kondova Ivanela
Bogers Willy
Verschoor Ernst J
author_sort Niphuis Henk
title Detection and characterization of two chimpanzee polyomavirus genotypes from different subspecies
title_short Detection and characterization of two chimpanzee polyomavirus genotypes from different subspecies
title_full Detection and characterization of two chimpanzee polyomavirus genotypes from different subspecies
title_fullStr Detection and characterization of two chimpanzee polyomavirus genotypes from different subspecies
title_full_unstemmed Detection and characterization of two chimpanzee polyomavirus genotypes from different subspecies
title_sort detection and characterization of two chimpanzee polyomavirus genotypes from different subspecies
publisher BMC
series Virology Journal
issn 1743-422X
publishDate 2010-11-01
description <p>Abstract</p> <p>The complete nucleotide sequences of three chimpanzee polyomavirus genetic variants were determined. Phylogenetic analysis indicated that the viruses form two different genotypes of ChPyV. Comparison with other primate polyomaviruses revealed a putative agnogene, and an unusually long VP1 open reading frame. The transcriptional control regions (TCR) of the viruses were extremely short (155 nucleotides), and highly conserved amongst the genotypes. Analysis of the TCR from different chimpanzee subspecies, and from a series of tissues from five individuals confirmed its genetic stability, and also indicates that double-infections with different genotypes can occur.</p>
url http://www.virologyj.com/content/7/1/347
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AT groenewoudmarlousj detectionandcharacterizationoftwochimpanzeepolyomavirusgenotypesfromdifferentsubspecies
AT fagrouchzahra detectionandcharacterizationoftwochimpanzeepolyomavirusgenotypesfromdifferentsubspecies
AT deuzingilona detectionandcharacterizationoftwochimpanzeepolyomavirusgenotypesfromdifferentsubspecies
AT kondovaivanela detectionandcharacterizationoftwochimpanzeepolyomavirusgenotypesfromdifferentsubspecies
AT bogerswilly detectionandcharacterizationoftwochimpanzeepolyomavirusgenotypesfromdifferentsubspecies
AT verschoorernstj detectionandcharacterizationoftwochimpanzeepolyomavirusgenotypesfromdifferentsubspecies
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