The Differential Effects of Anti-Diabetic Thiazolidinedione on Prostate Cancer Progression Are Linked to the TR4 Nuclear Receptor Expression Status
The insulin sensitizers, thiazolidinediones (TZDs), have been used as anti-diabetic drugs since the discovery of their ability to alter insulin resistance through transactivation of peroxisome proliferator-activated receptors (PPARs). However, their side effects in hepatitis, cardiovascular diseases...
Main Authors: | Shin-Jen Lin, Chang-Yi Lin, Dong-Rong Yang, Kouji Izumi, Emily Yan, Xiaodan Niu, Hong-Chiang Chang, Hiroshi Miyamoto, Nancy Wang, Gonghui Li, Chawnshang Chang |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2015-04-01
|
Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558615000317 |
Similar Items
-
TR4 nuclear receptor different roles in prostate cancer progression
by: Shin-Jen eLin, et al.
Published: (2015-05-01) -
Reduced osteoblast activity in the mice lacking TR4 nuclear receptor leads to osteoporosis
by: Lin Shin-Jen, et al.
Published: (2012-06-01) -
Correction to: Targeting TR4 nuclear receptor suppresses prostate cancer invasion via reduction of infiltrating acrophages with alteration of the TIMP-1/MMP2/MMP9 signals
by: Xianfan Ding, et al.
Published: (2020-05-01) -
The roles of testicular nuclear receptor 4 (TR4) in male fertility-priapism and sexual behavior defects in TR4 knockout mice
by: Bao Bo-Ying, et al.
Published: (2011-10-01) -
Effects of Thiazolidinedione and New Antidiabetic Agents on Stroke
by: Chang Ho Ahn, et al.
Published: (2019-05-01)