Randomised controlled trials of iron chelators for the treatment of cardiac siderosis in thalassaemia major

Randomised controlled trials of iron chelators for the treatment of cardiac siderosis in thalassaemia major

In conditions requiring repeated blood transfusion or where iron metabolism is abnormal, heart failure may result from accumulation of iron in the heart (cardiac siderosis). Death due to heart failure from cardiac iron overload has accounted for considerable early mortality in β-thalassemia major....

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Bibliographic Details
Main Authors: Arun John Baksi, Dudley J Pennell
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Pharmacology
Subjects:
Iron
Cardiac siderosis
chelation trials
T2* imaging
thalassaemia
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00217/full

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