CLINICALLY ISOLATED SYNDROME IN CHILDREN AND ADOLESCENTS — RISK FACTORS FOR MULTIPLE SCLEROSIS AND PROSPECTS OF USING INTRAMUSCULAR INTERFERON β-1A

The first demyelinating episode in the structure of multiple sclerosis is called clinically isolated syndrome, that is the clinical debut of the disease requiring an extensive differential diagnostic search and identification of long-term therapeutic tactics. It is well-known that experience of pres...

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Main Authors: O.V. Bykova, A.N. Platonova, N.N. Shatilova, A.V. Anikin, L.M. Kuzenkova
Format: Article
Language:English
Published: Paediatrician Publishers, LLC 2010-05-01
Series:Pediatričeskaâ Farmakologiâ
Online Access:https://pf.spr-journal.ru/jour/article/view/1152
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spelling doaj-b2fb2d47fbab43f38eacc860d19bfeca2020-11-25T01:30:16ZengPaediatrician Publishers, LLCPediatričeskaâ Farmakologiâ1727-57762500-30892010-05-017391941147CLINICALLY ISOLATED SYNDROME IN CHILDREN AND ADOLESCENTS — RISK FACTORS FOR MULTIPLE SCLEROSIS AND PROSPECTS OF USING INTRAMUSCULAR INTERFERON β-1AO.V. Bykova0A.N. Platonova1N.N. Shatilova2A.V. Anikin3L.M. Kuzenkova4Scientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowThe first demyelinating episode in the structure of multiple sclerosis is called clinically isolated syndrome, that is the clinical debut of the disease requiring an extensive differential diagnostic search and identification of long-term therapeutic tactics. It is well-known that experience of prescribing interferon β to adult patients at this earliest stage in the disease results in a substantially improved long-term disability prognosis. At the same time, promising techniques for an early launch of the biologic response modifier therapy have not yet found sufficient application in children and adolescents with multiple sclerosis.Key words: multiple sclerosis, clinically isolated syndrome, children, adolescents, interferon β.  (Pediatric Pharmacology. – 2010; 7(3):91-94)https://pf.spr-journal.ru/jour/article/view/1152
collection DOAJ
language English
format Article
sources DOAJ
author O.V. Bykova
A.N. Platonova
N.N. Shatilova
A.V. Anikin
L.M. Kuzenkova
spellingShingle O.V. Bykova
A.N. Platonova
N.N. Shatilova
A.V. Anikin
L.M. Kuzenkova
CLINICALLY ISOLATED SYNDROME IN CHILDREN AND ADOLESCENTS — RISK FACTORS FOR MULTIPLE SCLEROSIS AND PROSPECTS OF USING INTRAMUSCULAR INTERFERON β-1A
Pediatričeskaâ Farmakologiâ
author_facet O.V. Bykova
A.N. Platonova
N.N. Shatilova
A.V. Anikin
L.M. Kuzenkova
author_sort O.V. Bykova
title CLINICALLY ISOLATED SYNDROME IN CHILDREN AND ADOLESCENTS — RISK FACTORS FOR MULTIPLE SCLEROSIS AND PROSPECTS OF USING INTRAMUSCULAR INTERFERON β-1A
title_short CLINICALLY ISOLATED SYNDROME IN CHILDREN AND ADOLESCENTS — RISK FACTORS FOR MULTIPLE SCLEROSIS AND PROSPECTS OF USING INTRAMUSCULAR INTERFERON β-1A
title_full CLINICALLY ISOLATED SYNDROME IN CHILDREN AND ADOLESCENTS — RISK FACTORS FOR MULTIPLE SCLEROSIS AND PROSPECTS OF USING INTRAMUSCULAR INTERFERON β-1A
title_fullStr CLINICALLY ISOLATED SYNDROME IN CHILDREN AND ADOLESCENTS — RISK FACTORS FOR MULTIPLE SCLEROSIS AND PROSPECTS OF USING INTRAMUSCULAR INTERFERON β-1A
title_full_unstemmed CLINICALLY ISOLATED SYNDROME IN CHILDREN AND ADOLESCENTS — RISK FACTORS FOR MULTIPLE SCLEROSIS AND PROSPECTS OF USING INTRAMUSCULAR INTERFERON β-1A
title_sort clinically isolated syndrome in children and adolescents — risk factors for multiple sclerosis and prospects of using intramuscular interferon β-1a
publisher Paediatrician Publishers, LLC
series Pediatričeskaâ Farmakologiâ
issn 1727-5776
2500-3089
publishDate 2010-05-01
description The first demyelinating episode in the structure of multiple sclerosis is called clinically isolated syndrome, that is the clinical debut of the disease requiring an extensive differential diagnostic search and identification of long-term therapeutic tactics. It is well-known that experience of prescribing interferon β to adult patients at this earliest stage in the disease results in a substantially improved long-term disability prognosis. At the same time, promising techniques for an early launch of the biologic response modifier therapy have not yet found sufficient application in children and adolescents with multiple sclerosis.Key words: multiple sclerosis, clinically isolated syndrome, children, adolescents, interferon β.  (Pediatric Pharmacology. – 2010; 7(3):91-94)
url https://pf.spr-journal.ru/jour/article/view/1152
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