Association between Periodontal Disease and Systemic Inflammatory Conditions Using Electronic Health Records: A Pilot Study
Aims: To investigate the association between periodontal disease and systemic inflammatory conditions and examine the link between medical conditions and the extent of missing teeth in a large population. Methods: In this retrospective study, a total of 4890 randomly selected patients who had attend...
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doaj-b2fdef327d7e43df80d125d1ea2050fe2021-04-04T23:00:05ZengMDPI AGAntibiotics2079-63822021-04-011038638610.3390/antibiotics10040386Association between Periodontal Disease and Systemic Inflammatory Conditions Using Electronic Health Records: A Pilot StudyGeorgios S. Chatzopoulos0Alejandro Cisneros1Miguel Sanchez2Larry F. Wolff3Division of Periodontology, Department of Developmental and Surgical Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN 55455, USADivision of Periodontology, Department of Developmental and Surgical Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN 55455, USADivision of Periodontology, Department of Developmental and Surgical Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN 55455, USADivision of Periodontology, Department of Developmental and Surgical Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN 55455, USAAims: To investigate the association between periodontal disease and systemic inflammatory conditions and examine the link between medical conditions and the extent of missing teeth in a large population. Methods: In this retrospective study, a total of 4890 randomly selected patients who had attended the University of Minnesota dental clinics were analyzed. Severity of periodontal disease was determined based on the percentage of bone loss, evaluated through the examination of a full-mouth intraoral series of radiographs. The number of missing teeth was calculated from the examined radiographs, while ten systemic inflammatory conditions were extracted from patients’ self-reported medical histories. Results: Moderate bone loss was observed in 730 (14.9%) and severe in 323 (6.6%) patients of the total population, while the mean number of missing teeth was 3.54 ± 3.93. The prevalence of systemic conditions and tobacco use were gender-dependent (<i>p</i> < 0.05). Regression analysis showed that hypertension, arthritis, asthma, diabetes and HIV were associated significantly with the severity of bone loss, while diabetes and lupus with the extent of missing teeth. Conclusions: The findings reported in our study add to this body of knowledge, strengthening the association between periodontal disease with systemic inflammatory conditions.https://www.mdpi.com/2079-6382/10/4/386epidemiologyinflammationoral-systemic diseaseperiodontal diseasetooth loss |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Georgios S. Chatzopoulos Alejandro Cisneros Miguel Sanchez Larry F. Wolff |
spellingShingle |
Georgios S. Chatzopoulos Alejandro Cisneros Miguel Sanchez Larry F. Wolff Association between Periodontal Disease and Systemic Inflammatory Conditions Using Electronic Health Records: A Pilot Study Antibiotics epidemiology inflammation oral-systemic disease periodontal disease tooth loss |
author_facet |
Georgios S. Chatzopoulos Alejandro Cisneros Miguel Sanchez Larry F. Wolff |
author_sort |
Georgios S. Chatzopoulos |
title |
Association between Periodontal Disease and Systemic Inflammatory Conditions Using Electronic Health Records: A Pilot Study |
title_short |
Association between Periodontal Disease and Systemic Inflammatory Conditions Using Electronic Health Records: A Pilot Study |
title_full |
Association between Periodontal Disease and Systemic Inflammatory Conditions Using Electronic Health Records: A Pilot Study |
title_fullStr |
Association between Periodontal Disease and Systemic Inflammatory Conditions Using Electronic Health Records: A Pilot Study |
title_full_unstemmed |
Association between Periodontal Disease and Systemic Inflammatory Conditions Using Electronic Health Records: A Pilot Study |
title_sort |
association between periodontal disease and systemic inflammatory conditions using electronic health records: a pilot study |
publisher |
MDPI AG |
series |
Antibiotics |
issn |
2079-6382 |
publishDate |
2021-04-01 |
description |
Aims: To investigate the association between periodontal disease and systemic inflammatory conditions and examine the link between medical conditions and the extent of missing teeth in a large population. Methods: In this retrospective study, a total of 4890 randomly selected patients who had attended the University of Minnesota dental clinics were analyzed. Severity of periodontal disease was determined based on the percentage of bone loss, evaluated through the examination of a full-mouth intraoral series of radiographs. The number of missing teeth was calculated from the examined radiographs, while ten systemic inflammatory conditions were extracted from patients’ self-reported medical histories. Results: Moderate bone loss was observed in 730 (14.9%) and severe in 323 (6.6%) patients of the total population, while the mean number of missing teeth was 3.54 ± 3.93. The prevalence of systemic conditions and tobacco use were gender-dependent (<i>p</i> < 0.05). Regression analysis showed that hypertension, arthritis, asthma, diabetes and HIV were associated significantly with the severity of bone loss, while diabetes and lupus with the extent of missing teeth. Conclusions: The findings reported in our study add to this body of knowledge, strengthening the association between periodontal disease with systemic inflammatory conditions. |
topic |
epidemiology inflammation oral-systemic disease periodontal disease tooth loss |
url |
https://www.mdpi.com/2079-6382/10/4/386 |
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