Changes in T-Tubules and Sarcoplasmic Reticulum in Ventricular Myocytes in Early Cardiac Hypertrophy in a Pressure Overload Rat Model

Changes in T-Tubules and Sarcoplasmic Reticulum in Ventricular Myocytes in Early Cardiac Hypertrophy in a Pressure Overload Rat Model

Background/Aims: Pressure-overload (PO) causes cardiac hypertrophy (CH), and eventually leads to heart failure (HF). HF ventricular myocytes present transverse-tubules (TT) loss or disarrangement and decreased sarcoplasmic reticulum (SR) density, and both contribute to altered Ca2+ signaling and hea...

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Bibliographic Details
Main Authors: Perla Pérez-Treviño, Jorge Pérez-Treviño, Cuauhtémoc Borja-Villa, Noemí García, Julio Altamirano
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Transverse tubules
Cardiac hypertrophy
Calcium signaling
Pressure overload
Fluorescence recovery after photobleach
Sarcoplasmic reticulum
Online Access:http://www.karger.com/Article/FullText/430254

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