Liraglutide to Improve corONary haemodynamics during Exercise streSS (LIONESS): a double-blind randomised placebo-controlled crossover trial

Liraglutide to Improve corONary haemodynamics during Exercise streSS (LIONESS): a double-blind randomised placebo-controlled crossover trial

Abstract Background Glucagon-like peptide-1 receptor (GLP-1R) activation may improve myocardial performance in the context of ischaemia, independent of glycaemic control, in individuals with and without type 2 diabetes mellitus. Methods The LIONESS trial was a single-centre randomised double-blind p...

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Bibliographic Details
Main Authors: Aung Myat, Simon R. Redwood, Satpal Arri, Bernard J. Gersh, Deepak L. Bhatt, Michael S. Marber
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Liraglutide
Glucagon-like peptide-1 receptor agonist
Myocardial ischaemia
Chronic stable angina
Coronary artery disease
Incretin
Online Access:https://doi.org/10.1186/s13098-021-00635-6

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