The effect of the subclinical small ruminant lentivirus infection of female goats on the growth of kids.
A longitudinal observational study was carried out to evaluate the influence of prenatal exposure to small ruminant lentivirus(SRLV)-infected does on the body weight (BWT) of young kids. The study was carried out in years 2001-2017 in the research dairy goat herd. Goats in the herd were regularly se...
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doaj-b3825d61da484cbd934b3d0c65be1aea2021-03-03T21:37:25ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-01153e023061710.1371/journal.pone.0230617The effect of the subclinical small ruminant lentivirus infection of female goats on the growth of kids.Tomasz NalbertMichał CzopowiczOlga Szaluś-JordanowLucjan WitkowskiAgata MorozMarcin MickiewiczIwona Markowska-DanielDanuta SłoniewskaEmilia BagnickaJarosław KabaA longitudinal observational study was carried out to evaluate the influence of prenatal exposure to small ruminant lentivirus(SRLV)-infected does on the body weight (BWT) of young kids. The study was carried out in years 2001-2017 in the research dairy goat herd. Goats in the herd were regularly serologically tested and individuals showing clinical signs of caprine arthritis-encephalitis (CAE) were promptly culled. As a result all goats enrolled in the study were asymptomatic. Moreover, kids were weaned immediately after birth, fed on bovine colostrum and kept in strict separation from mothers to prevent SRLV lactogenic transmission. Kids were weighed immediately after birth, and then 1-3 times within the first 3 months of life. In total 620 goat kids were weighed at least once, excluding weighing at birth, providing 992 BWT records. The mixed linear model including four variables fitted as random effects (doe, kid, the year of kid's birth and the exact age of a kid at weighing) and four potential confounders fitted as fixed effects (parity, kid's sex, litter size and birth body weight) was developed and showed that BWT was not significantly associated with SRLV serological status of a doe, regardless of the time for which does had been infected before the delivery of the kid (p = 0.242). This study provides strong evidence that kids born to SRLV-infected does grow equally well as kids from uninfected does, provided that the lactogenic viral transmission is prevented by maintaining strict separation between the offspring and mothers. This observation is important for choosing the most optimal strategy of CAE control in a goat herd.https://doi.org/10.1371/journal.pone.0230617 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Tomasz Nalbert Michał Czopowicz Olga Szaluś-Jordanow Lucjan Witkowski Agata Moroz Marcin Mickiewicz Iwona Markowska-Daniel Danuta Słoniewska Emilia Bagnicka Jarosław Kaba |
spellingShingle |
Tomasz Nalbert Michał Czopowicz Olga Szaluś-Jordanow Lucjan Witkowski Agata Moroz Marcin Mickiewicz Iwona Markowska-Daniel Danuta Słoniewska Emilia Bagnicka Jarosław Kaba The effect of the subclinical small ruminant lentivirus infection of female goats on the growth of kids. PLoS ONE |
author_facet |
Tomasz Nalbert Michał Czopowicz Olga Szaluś-Jordanow Lucjan Witkowski Agata Moroz Marcin Mickiewicz Iwona Markowska-Daniel Danuta Słoniewska Emilia Bagnicka Jarosław Kaba |
author_sort |
Tomasz Nalbert |
title |
The effect of the subclinical small ruminant lentivirus infection of female goats on the growth of kids. |
title_short |
The effect of the subclinical small ruminant lentivirus infection of female goats on the growth of kids. |
title_full |
The effect of the subclinical small ruminant lentivirus infection of female goats on the growth of kids. |
title_fullStr |
The effect of the subclinical small ruminant lentivirus infection of female goats on the growth of kids. |
title_full_unstemmed |
The effect of the subclinical small ruminant lentivirus infection of female goats on the growth of kids. |
title_sort |
effect of the subclinical small ruminant lentivirus infection of female goats on the growth of kids. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2020-01-01 |
description |
A longitudinal observational study was carried out to evaluate the influence of prenatal exposure to small ruminant lentivirus(SRLV)-infected does on the body weight (BWT) of young kids. The study was carried out in years 2001-2017 in the research dairy goat herd. Goats in the herd were regularly serologically tested and individuals showing clinical signs of caprine arthritis-encephalitis (CAE) were promptly culled. As a result all goats enrolled in the study were asymptomatic. Moreover, kids were weaned immediately after birth, fed on bovine colostrum and kept in strict separation from mothers to prevent SRLV lactogenic transmission. Kids were weighed immediately after birth, and then 1-3 times within the first 3 months of life. In total 620 goat kids were weighed at least once, excluding weighing at birth, providing 992 BWT records. The mixed linear model including four variables fitted as random effects (doe, kid, the year of kid's birth and the exact age of a kid at weighing) and four potential confounders fitted as fixed effects (parity, kid's sex, litter size and birth body weight) was developed and showed that BWT was not significantly associated with SRLV serological status of a doe, regardless of the time for which does had been infected before the delivery of the kid (p = 0.242). This study provides strong evidence that kids born to SRLV-infected does grow equally well as kids from uninfected does, provided that the lactogenic viral transmission is prevented by maintaining strict separation between the offspring and mothers. This observation is important for choosing the most optimal strategy of CAE control in a goat herd. |
url |
https://doi.org/10.1371/journal.pone.0230617 |
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