Effect size, sample size and power of forced swim test assays in mice: Guidelines for investigators to optimize reproducibility.
A recent flood of publications has documented serious problems in scientific reproducibility, power, and reporting of biomedical articles, yet scientists persist in their usual practices. Why? We examined a popular and important preclinical assay, the Forced Swim Test (FST) in mice used to test puta...
Main Authors: | Neil R Smalheiser, Elena E Graetz, Zhou Yu, Jing Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0243668 |
Similar Items
-
Size matters: how sample size affects the reproducibility and specificity of gene set analysis
by: Farhad Maleki, et al.
Published: (2019-10-01) -
The effects of temperature and size on swimming in fish
by: Archer, Stephen D.
Published: (1990) -
Analysis of Bayesian posterior significance and effect size indices for the two-sample t-test to support reproducible medical research
by: Riko Kelter
Published: (2020-04-01) -
Some Practical Guidelines for Effective Sample-Size Determination in Observational Studies
by: Wan Muhamad Amir W Ahmad, et al.
Published: (2012-08-01) -
Empirical Sample Size Guidelines for Use of Latent Difference Score Mediation
by: Lockhart, G., et al.
Published: (2019)