Glycogen Metabolism Supports Early Glycolytic Reprogramming and Activation in Dendritic Cells in Response to Both TLR and Syk-Dependent CLR Agonists

Glycogen Metabolism Supports Early Glycolytic Reprogramming and Activation in Dendritic Cells in Response to Both TLR and Syk-Dependent CLR Agonists

Dendritic cells (DCs) increase their metabolic dependence on glucose and glycolysis to support their maturation, activation-associated cytokine production, and T-cell stimulatory capacity. We have previously shown that this increase in glucose metabolism can be initiated by both Toll-like receptor (...

Full description

Bibliographic Details
Main Authors: Kylie D. Curtis, Portia R. Smith, Hannah W. Despres, Julia P. Snyder, Tyler C. Hogan, Princess D. Rodriguez, Eyal Amiel
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
glycolysis
glycogen
glucose
dendritic cells
metabolism
innate immunity
Online Access:https://www.mdpi.com/2073-4409/9/3/715

Internet

https://www.mdpi.com/2073-4409/9/3/715

Similar Items