Organoid-derived C-Kit+/SSEA4− human retinal progenitor cells promote a protective retinal microenvironment during transplantation in rodents
Stem cell transplantation to treat retinal degeneration could be limited by the degenerative microenvironment. Here, the authors show that C-Kit+/SSEA4– progenitor cells enriched from human embryonic stem cell derived retinal organoids protect retinal structure, suppress microglial activation, glios...
Full description
Bibliographic Details
| Main Authors: |
Ting Zou,
Lixiong Gao,
Yuxiao Zeng,
Qiyou Li,
Yijian Li,
Siyu Chen,
Xisu Hu,
Xi Chen,
Caiyun Fu,
Haiwei Xu,
Zheng Qin Yin |
|---|
| Format: | Article
|
|---|
| Language: | English |
|---|
| Published: |
Nature Publishing Group
2019-03-01
|
|---|
| Series: | Nature Communications
|
|---|
| Online Access: | https://doi.org/10.1038/s41467-019-08961-0
|
|---|
