Diketoacetonylphenalenone, Derived from Hawaiian Volcanic Soil-Associated Fungus <i>Penicillium herquei</i> FT729, Regulates T Cell Activation via Nuclear Factor-κB and Mitogen-Activated Protein Kinase Pathway

Diketoacetonylphenalenone, Derived from Hawaiian Volcanic Soil-Associated Fungus <i>Penicillium herquei</i> FT729, Regulates T Cell Activation via Nuclear Factor-κB and Mitogen-Activated Protein Kinase Pathway

In immunological responses, controlling excessive T cell activity is critical for immunological homeostasis maintenance. Diketoacetonylphenalenone, derived from Hawaiian volcanic soil-associated fungus <i>Penicillium herquei</i> FT729, possesses moderate anti-inflammatory activity in RAW...

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Bibliographic Details
Main Authors: Hyun-Su Lee, Jae Sik Yu, Ki Hyun Kim, Gil-Saeng Jeong
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Molecules
Subjects:
T cells
<i>Penicillium herquei</i> FT729
immunosuppressive
Online Access:https://www.mdpi.com/1420-3049/25/22/5374

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