Tibial dyschondroplasia is highly associated with suppression of tibial angiogenesis through regulating the HIF-1α/VEGF/VEGFR signaling pathway in chickens

Abstract Tibial dyschondroplasia (TD) is an intractable poultry problem that is characterized by the appearance of non-vascularized and non-mineralized cartilage masses in tibial growth plates (TGPs). However, the role of angiogenesis inhibition in the occurrence of TD remains unknown. In this study...

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Bibliographic Details
Main Authors: Shu-cheng Huang, Mujeeb Ur Rehman, Yan-fang Lan, Gang Qiu, Hui Zhang, Muhammad Kashif Iqbal, Hou-qiang Luo, Khalid Mehmood, Li-hong Zhang, Jia-kui Li
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-09664-6

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