Fibroblast Growth Factor Receptor Functions in Glioblastoma

Fibroblast Growth Factor Receptor Functions in Glioblastoma

Glioblastoma is the most lethal brain cancer in adults, with no known cure. This cancer is characterized by a pronounced genetic heterogeneity, but aberrant activation of receptor tyrosine kinase signaling is among the most frequent molecular alterations in glioblastoma. Somatic mutations of fibrobl...

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Bibliographic Details
Main Authors: Ana Jimenez-Pascual, Florian A. Siebzehnrubl
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cells
Subjects:
FGFR
review
malignant glioma
brain cancer
astrocytoma
fibroblast growth factor
Online Access:https://www.mdpi.com/2073-4409/8/7/715

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