Somatic synonymous mutations in regulatory elements contribute to the genetic aetiology of melanoma
Abstract Background Non-synonymous mutations altering tumor suppressor genes and oncogenes are widely studied. However, synonymous mutations, which do not alter the protein sequence, are rarely investigated in melanoma genome studies. Methods We explored the role of somatic synonymous mutations in m...
Main Authors: | Di Zhang, Junfeng Xia |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-04-01
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Series: | BMC Medical Genomics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12920-020-0685-2 |
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