Differential Proteomic Analysis of Nuclear Matrix in Muscle-Invasive Bladder Cancer: Potential to Improve Diagnosis and Prognosis

Differential Proteomic Analysis of Nuclear Matrix in Muscle-Invasive Bladder Cancer: Potential to Improve Diagnosis and Prognosis

Introduction: Although several molecular markers for bladder cancer have been identified, at present little information on prognostic biomarkers is available in the literature. Prognostication of this tumor is largely based on clinicopathological characteristics. Our aim was to identify nuclear matr...

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Main Authors: Paola Barboro, Alessandra Rubagotti, Paola Orecchia, Bruno Spina, Mauro Truini, Erica Repaci, Giorgio Carmignani, Andrea Romagnoli, Carlo Introini, Francesco Boccardo, Barbara Carnemolla, Cecilia Balbi
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.1155/2008/686940
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spelling doaj-b3fb52c6cc27438fb183417c591983122020-11-25T00:45:00ZengHindawi LimitedCellular Oncology1570-58701875-86062008-01-01301132610.1155/2008/686940Differential Proteomic Analysis of Nuclear Matrix in Muscle-Invasive Bladder Cancer: Potential to Improve Diagnosis and PrognosisPaola Barboro0Alessandra Rubagotti1Paola Orecchia2Bruno Spina3Mauro Truini4Erica Repaci5Giorgio Carmignani6Andrea Romagnoli7Carlo Introini8Francesco Boccardo9Barbara Carnemolla10Cecilia Balbi11National Cancer Research Institute, Genoa, ItalyNational Cancer Research Institute, Genoa, ItalyInstitute Giannina Gaslini, Genoa, ItalyNational Cancer Research Institute, Genoa, ItalyNational Cancer Research Institute, Genoa, ItalyNational Cancer Research Institute, Genoa, ItalyDepartment of Urology, University of Genoa, ItalyDepartment of Urology, University of Genoa, ItalyNational Cancer Research Institute, Genoa, ItalyNational Cancer Research Institute, Genoa, ItalyNational Cancer Research Institute, Genoa, ItalyNational Cancer Research Institute, Genoa, ItalyIntroduction: Although several molecular markers for bladder cancer have been identified, at present little information on prognostic biomarkers is available in the literature. Prognostication of this tumor is largely based on clinicopathological characteristics. Our aim was to identify nuclear matrix (NM) proteins that might serve to better characterize the phenotype of the invasive bladder cancer and to investigate their diagnostic and prognostic roles.http://dx.doi.org/10.1155/2008/686940
collection DOAJ
language English
format Article
sources DOAJ
author Paola Barboro
Alessandra Rubagotti
Paola Orecchia
Bruno Spina
Mauro Truini
Erica Repaci
Giorgio Carmignani
Andrea Romagnoli
Carlo Introini
Francesco Boccardo
Barbara Carnemolla
Cecilia Balbi
spellingShingle Paola Barboro
Alessandra Rubagotti
Paola Orecchia
Bruno Spina
Mauro Truini
Erica Repaci
Giorgio Carmignani
Andrea Romagnoli
Carlo Introini
Francesco Boccardo
Barbara Carnemolla
Cecilia Balbi
Differential Proteomic Analysis of Nuclear Matrix in Muscle-Invasive Bladder Cancer: Potential to Improve Diagnosis and Prognosis
Cellular Oncology
author_facet Paola Barboro
Alessandra Rubagotti
Paola Orecchia
Bruno Spina
Mauro Truini
Erica Repaci
Giorgio Carmignani
Andrea Romagnoli
Carlo Introini
Francesco Boccardo
Barbara Carnemolla
Cecilia Balbi
author_sort Paola Barboro
title Differential Proteomic Analysis of Nuclear Matrix in Muscle-Invasive Bladder Cancer: Potential to Improve Diagnosis and Prognosis
title_short Differential Proteomic Analysis of Nuclear Matrix in Muscle-Invasive Bladder Cancer: Potential to Improve Diagnosis and Prognosis
title_full Differential Proteomic Analysis of Nuclear Matrix in Muscle-Invasive Bladder Cancer: Potential to Improve Diagnosis and Prognosis
title_fullStr Differential Proteomic Analysis of Nuclear Matrix in Muscle-Invasive Bladder Cancer: Potential to Improve Diagnosis and Prognosis
title_full_unstemmed Differential Proteomic Analysis of Nuclear Matrix in Muscle-Invasive Bladder Cancer: Potential to Improve Diagnosis and Prognosis
title_sort differential proteomic analysis of nuclear matrix in muscle-invasive bladder cancer: potential to improve diagnosis and prognosis
publisher Hindawi Limited
series Cellular Oncology
issn 1570-5870
1875-8606
publishDate 2008-01-01
description Introduction: Although several molecular markers for bladder cancer have been identified, at present little information on prognostic biomarkers is available in the literature. Prognostication of this tumor is largely based on clinicopathological characteristics. Our aim was to identify nuclear matrix (NM) proteins that might serve to better characterize the phenotype of the invasive bladder cancer and to investigate their diagnostic and prognostic roles.
url http://dx.doi.org/10.1155/2008/686940
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