Food Environments and Hepatocellular Carcinoma Incidence
Research into the potential impact of the food environment on liver cancer incidence has been limited, though there is evidence showing that specific foods and nutrients may be potential risk or preventive factors. Data on hepatocellular carcinoma (HCC) cases were obtained from the Surveillance, Epi...
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doaj-b3fd1137996448a693fb10972c9617e92021-06-01T01:17:10ZengMDPI AGInternational Journal of Environmental Research and Public Health1661-78271660-46012021-05-01185740574010.3390/ijerph18115740Food Environments and Hepatocellular Carcinoma IncidenceMimi Ton0Michael J. Widener1Peter James2Trang VoPham3Department of Epidemiology, University of Washington School of Public Health, 3980 15th Ave NE, Seattle, WA 98195, USADepartment of Geography and Planning, University of Toronto, 100 St. George Street, Toronto, ON M5S 3G3, CanadaDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 401 Park Drive, Boston, MA 02215, USADepartment of Epidemiology, University of Washington School of Public Health, 3980 15th Ave NE, Seattle, WA 98195, USAResearch into the potential impact of the food environment on liver cancer incidence has been limited, though there is evidence showing that specific foods and nutrients may be potential risk or preventive factors. Data on hepatocellular carcinoma (HCC) cases were obtained from the Surveillance, Epidemiology, and End Results (SEER) cancer registries. The county-level food environment was assessed using the Modified Retail Food Environment Index (mRFEI), a continuous score that measures the number of healthy and less healthy food retailers within counties. Poisson regression with robust variance estimation was used to calculate incidence rate ratios (IRRs) and 95% confidence intervals (CIs) for the association between mRFEI scores and HCC risk, adjusting for individual- and county-level factors. The county-level food environment was not associated with HCC risk after adjustment for individual-level age at diagnosis, sex, race/ethnicity, year, and SEER registry and county-level measures for health conditions, lifestyle factors, and socioeconomic status (adjusted IRR: 0.99, 95% CI: 0.96, 1.01). The county-level food environment, measured using mRFEI scores, was not associated with HCC risk.https://www.mdpi.com/1660-4601/18/11/5740food environmentsliver cancerepidemiology |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mimi Ton Michael J. Widener Peter James Trang VoPham |
spellingShingle |
Mimi Ton Michael J. Widener Peter James Trang VoPham Food Environments and Hepatocellular Carcinoma Incidence International Journal of Environmental Research and Public Health food environments liver cancer epidemiology |
author_facet |
Mimi Ton Michael J. Widener Peter James Trang VoPham |
author_sort |
Mimi Ton |
title |
Food Environments and Hepatocellular Carcinoma Incidence |
title_short |
Food Environments and Hepatocellular Carcinoma Incidence |
title_full |
Food Environments and Hepatocellular Carcinoma Incidence |
title_fullStr |
Food Environments and Hepatocellular Carcinoma Incidence |
title_full_unstemmed |
Food Environments and Hepatocellular Carcinoma Incidence |
title_sort |
food environments and hepatocellular carcinoma incidence |
publisher |
MDPI AG |
series |
International Journal of Environmental Research and Public Health |
issn |
1661-7827 1660-4601 |
publishDate |
2021-05-01 |
description |
Research into the potential impact of the food environment on liver cancer incidence has been limited, though there is evidence showing that specific foods and nutrients may be potential risk or preventive factors. Data on hepatocellular carcinoma (HCC) cases were obtained from the Surveillance, Epidemiology, and End Results (SEER) cancer registries. The county-level food environment was assessed using the Modified Retail Food Environment Index (mRFEI), a continuous score that measures the number of healthy and less healthy food retailers within counties. Poisson regression with robust variance estimation was used to calculate incidence rate ratios (IRRs) and 95% confidence intervals (CIs) for the association between mRFEI scores and HCC risk, adjusting for individual- and county-level factors. The county-level food environment was not associated with HCC risk after adjustment for individual-level age at diagnosis, sex, race/ethnicity, year, and SEER registry and county-level measures for health conditions, lifestyle factors, and socioeconomic status (adjusted IRR: 0.99, 95% CI: 0.96, 1.01). The county-level food environment, measured using mRFEI scores, was not associated with HCC risk. |
topic |
food environments liver cancer epidemiology |
url |
https://www.mdpi.com/1660-4601/18/11/5740 |
work_keys_str_mv |
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