Dendritic cell-induced activation of latent HIV-1 provirus in actively proliferating primary T lymphocytes.

Dendritic cell-induced activation of latent HIV-1 provirus in actively proliferating primary T lymphocytes.

HIV-1 latency remains a formidable barrier towards virus eradication as therapeutic attempts to purge these reservoirs are so far unsuccessful. The pool of transcriptionally silent proviruses is established early in infection and persists for a lifetime, even when viral loads are suppressed below de...

Full description

Bibliographic Details
Main Authors: Renée M van der Sluis, Thijs van Montfort, Georgios Pollakis, Rogier W Sanders, Dave Speijer, Ben Berkhout, Rienk E Jeeninga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-03-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23555263/pdf/?tool=EBI

Similar Items

Similar Items