Variations in Orf3a protein of SARS-CoV-2 alter its structure and function

Variations in Orf3a protein of SARS-CoV-2 alter its structure and function

Severe acquired respiratory syndrome coronavirus 2 (SARS-CoV-2) rapidly spread worldwide and acquired multiple mutations in its genome. Orf3a, an accessory protein encoded by the genome of SARS-CoV-2, plays a significant role in viral infection and pathogenesis. In the present in-silico study, 15,92...

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Bibliographic Details
Main Authors: Gajendra Kumar Azad, Parimal Kumar Khan
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
SARS-CoV-2
Mutations
Orf3a
Protein stability
Protein disorder
B-cell epitopes
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821000273

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