ATM’s Role in the Repair of DNA Double-Strand Breaks

Ataxia telangiectasia mutated (ATM) is a central kinase that activates an extensive network of responses to cellular stress via a signaling role. ATM is activated by DNA double strand breaks (DSBs) and by oxidative stress, subsequently phosphorylating a plethora of target proteins. In the last sever...

Full description

Bibliographic Details
Main Authors: Atsushi Shibata, Penny A. Jeggo
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Genes
Subjects:
ATM
Online Access:https://www.mdpi.com/2073-4425/12/9/1370