ATM’s Role in the Repair of DNA Double-Strand Breaks
Ataxia telangiectasia mutated (ATM) is a central kinase that activates an extensive network of responses to cellular stress via a signaling role. ATM is activated by DNA double strand breaks (DSBs) and by oxidative stress, subsequently phosphorylating a plethora of target proteins. In the last sever...
Main Authors: | Atsushi Shibata, Penny A. Jeggo |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-08-01
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Series: | Genes |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4425/12/9/1370 |
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