The impact of endocrine disruptor chemicals on oocyte/embryo and clinical outcomes in IVF
The negative impact of endocrine-disrupting pesticides on human fertility is now a key issue in reproductive health. There are much fewer literature data about the impact of pesticide exposure on women than on men and very few studies of women participating in an in vitro fertilization (IVF) program...
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2020-06-01
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doaj-b440fef6255a4151aab175a25ad8272f2020-11-25T03:03:26ZengBioscientificaEndocrine Connections2049-36142049-36142020-06-0196R134R142https://doi.org/10.1530/EC-20-0135The impact of endocrine disruptor chemicals on oocyte/embryo and clinical outcomes in IVFRosalie Cabry0Philippe Merviel1Aicha Madkour2Elodie Lefranc3Florence Scheffler4Rachel Desailloud5Véronique Bach6Moncef Benkhalifa7Amiens University, Amiens, Haut-de-France, FranceBrest University, Brest, Bretagne, FranceMohammed V University of Rabat, Reproductive Medicine, Rabat, MoroccoAmiens University, Amiens, Haut-de-France, FranceAmiens University, Amiens, Haut-de-France, FranceAmiens University, Amiens, Haut-de-France, FranceAmiens University, Amiens, Haut-de-France, FranceAmiens University, Amiens, Haut-de-France, FranceThe negative impact of endocrine-disrupting pesticides on human fertility is now a key issue in reproductive health. There are much fewer literature data about the impact of pesticide exposure on women than on men and very few studies of women participating in an in vitro fertilization (IVF) programme. In the present review, we found that (1) various pesticides with an endocrine-disrupting action are associated with poor oocyte maturation and competency, embryonic defects and poor IVF outcomes, and (2) some pesticide compounds are linked to specific causes of female infe rtility, such as premature ovarian insufficiency, polycystic ovarian syndrome, and endometriosis. IVF participants living in agricultural regions should be informed about the fertility decline, low ongoing pregnancy rates, and elevated risk of miscarriage associated with exposure to high doses of pesticides.https://ec.bioscientifica.com/view/journals/ec/9/6/EC-20-0135.xmlendocrine disruptoroocyte-embryoclinical outcomeivf |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Rosalie Cabry Philippe Merviel Aicha Madkour Elodie Lefranc Florence Scheffler Rachel Desailloud Véronique Bach Moncef Benkhalifa |
spellingShingle |
Rosalie Cabry Philippe Merviel Aicha Madkour Elodie Lefranc Florence Scheffler Rachel Desailloud Véronique Bach Moncef Benkhalifa The impact of endocrine disruptor chemicals on oocyte/embryo and clinical outcomes in IVF Endocrine Connections endocrine disruptor oocyte-embryo clinical outcome ivf |
author_facet |
Rosalie Cabry Philippe Merviel Aicha Madkour Elodie Lefranc Florence Scheffler Rachel Desailloud Véronique Bach Moncef Benkhalifa |
author_sort |
Rosalie Cabry |
title |
The impact of endocrine disruptor chemicals on oocyte/embryo and clinical outcomes in IVF |
title_short |
The impact of endocrine disruptor chemicals on oocyte/embryo and clinical outcomes in IVF |
title_full |
The impact of endocrine disruptor chemicals on oocyte/embryo and clinical outcomes in IVF |
title_fullStr |
The impact of endocrine disruptor chemicals on oocyte/embryo and clinical outcomes in IVF |
title_full_unstemmed |
The impact of endocrine disruptor chemicals on oocyte/embryo and clinical outcomes in IVF |
title_sort |
impact of endocrine disruptor chemicals on oocyte/embryo and clinical outcomes in ivf |
publisher |
Bioscientifica |
series |
Endocrine Connections |
issn |
2049-3614 2049-3614 |
publishDate |
2020-06-01 |
description |
The negative impact of endocrine-disrupting pesticides on human fertility is now a key issue in reproductive health. There are much fewer literature data about the impact of pesticide exposure on women than on men and very few studies of women participating in an in vitro fertilization (IVF) programme. In the present review, we found that (1) various pesticides with an endocrine-disrupting action are associated with poor oocyte maturation and competency, embryonic defects and poor IVF outcomes, and (2) some pesticide compounds are linked to specific causes of female infe rtility, such as premature ovarian insufficiency, polycystic ovarian syndrome, and endometriosis. IVF participants living in agricultural regions should be informed about the fertility decline, low ongoing pregnancy rates, and elevated risk of miscarriage associated with exposure to high doses of pesticides. |
topic |
endocrine disruptor oocyte-embryo clinical outcome ivf |
url |
https://ec.bioscientifica.com/view/journals/ec/9/6/EC-20-0135.xml |
work_keys_str_mv |
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