The roles of replication-transcription conflict in mutagenesis and evolution of genome organization.
Replication-transcription conflicts promote mutagenesis and give rise to evolutionary signatures, with fundamental importance to genome stability ranging from bacteria to metastatic cancer cells. This review focuses on the interplay between replication-transcription conflicts and the evolution of ge...
Main Authors: | Jeremy W Schroeder, T Sabari Sankar, Jue D Wang, Lyle A Simmons |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-08-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1008987 |
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