The gut microbiome in konzo
Here, using metagenomic profiling in 180 individuals from the Democratic Republic of the Congo, the authors find associations between the gut microbiome and konzo, a neurodegenerative disease that mostly affects children and is caused by the consumption improperly processed cassava.
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Nature Publishing Group
2021-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-25694-1 |
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doaj-b46fefcdd6e94aef9529183f74cc56a92021-09-12T11:44:45ZengNature Publishing GroupNature Communications2041-17232021-09-0112111310.1038/s41467-021-25694-1The gut microbiome in konzoMatthew S. Bramble0Neerja Vashist1Arthur Ko2Sambhawa Priya3Céleste Musasa4Alban Mathieu5D’ Andre Spencer6Michel Lupamba Kasendue7Patrick Mamona Dilufwasayo8Kevin Karume9Joanna Nsibu10Hans Manya11Mary N. A. Uy12Brian Colwell13Michael Boivin14J. P. Banae Mayambu15Daniel Okitundu16Arnaud Droit17Dieudonné Mumba Ngoyi18Ran Blekhman19Desire Tshala-Katumbay20Eric Vilain21Center for Genetic Medicine Research, Children’s Research Institute, Children’s National HospitalCenter for Genetic Medicine Research, Children’s Research Institute, Children’s National HospitalDepartment of Medicine, David Geffen School of Medicine, University of California, Los AngelesDepartments of Genetics, Cell Biology, and Development, University of MinnesotaCenter for Genetic Medicine Research, Children’s Research Institute, Children’s National HospitalComputational Biology Laboratory, CHU de Québec - Université Laval Research CenterCenter for Genetic Medicine Research, Children’s Research Institute, Children’s National HospitalInstitut National de Recherche Biomédicale (INRB)Center for Genetic Medicine Research, Children’s Research Institute, Children’s National HospitalCenter for Genetic Medicine Research, Children’s Research Institute, Children’s National HospitalInstitut National de Recherche Biomédicale (INRB)Center for Genetic Medicine Research, Children’s Research Institute, Children’s National HospitalCenter for Genetic Medicine Research, Children’s Research Institute, Children’s National HospitalSchool of Public Health, Texas A&M UniversityDepartment of Psychiatry and Neurology & Ophthalmology, Michigan State UniversityMinistry of Health National Program on Nutrition (PRONANUT)Centre Neuro-Psychopathologique (CNPP), University of KinshasaComputational Biology Laboratory, CHU de Québec - Université Laval Research CenterInstitut National de Recherche Biomédicale (INRB)Departments of Genetics, Cell Biology, and Development, University of MinnesotaInstitut National de Recherche Biomédicale (INRB)Center for Genetic Medicine Research, Children’s Research Institute, Children’s National HospitalHere, using metagenomic profiling in 180 individuals from the Democratic Republic of the Congo, the authors find associations between the gut microbiome and konzo, a neurodegenerative disease that mostly affects children and is caused by the consumption improperly processed cassava.https://doi.org/10.1038/s41467-021-25694-1 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Matthew S. Bramble Neerja Vashist Arthur Ko Sambhawa Priya Céleste Musasa Alban Mathieu D’ Andre Spencer Michel Lupamba Kasendue Patrick Mamona Dilufwasayo Kevin Karume Joanna Nsibu Hans Manya Mary N. A. Uy Brian Colwell Michael Boivin J. P. Banae Mayambu Daniel Okitundu Arnaud Droit Dieudonné Mumba Ngoyi Ran Blekhman Desire Tshala-Katumbay Eric Vilain |
| spellingShingle |
Matthew S. Bramble Neerja Vashist Arthur Ko Sambhawa Priya Céleste Musasa Alban Mathieu D’ Andre Spencer Michel Lupamba Kasendue Patrick Mamona Dilufwasayo Kevin Karume Joanna Nsibu Hans Manya Mary N. A. Uy Brian Colwell Michael Boivin J. P. Banae Mayambu Daniel Okitundu Arnaud Droit Dieudonné Mumba Ngoyi Ran Blekhman Desire Tshala-Katumbay Eric Vilain The gut microbiome in konzo Nature Communications |
| author_facet |
Matthew S. Bramble Neerja Vashist Arthur Ko Sambhawa Priya Céleste Musasa Alban Mathieu D’ Andre Spencer Michel Lupamba Kasendue Patrick Mamona Dilufwasayo Kevin Karume Joanna Nsibu Hans Manya Mary N. A. Uy Brian Colwell Michael Boivin J. P. Banae Mayambu Daniel Okitundu Arnaud Droit Dieudonné Mumba Ngoyi Ran Blekhman Desire Tshala-Katumbay Eric Vilain |
| author_sort |
Matthew S. Bramble |
| title |
The gut microbiome in konzo |
| title_short |
The gut microbiome in konzo |
| title_full |
The gut microbiome in konzo |
| title_fullStr |
The gut microbiome in konzo |
| title_full_unstemmed |
The gut microbiome in konzo |
| title_sort |
gut microbiome in konzo |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2021-09-01 |
| description |
Here, using metagenomic profiling in 180 individuals from the Democratic Republic of the Congo, the authors find associations between the gut microbiome and konzo, a neurodegenerative disease that mostly affects children and is caused by the consumption improperly processed cassava. |
| url |
https://doi.org/10.1038/s41467-021-25694-1 |
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