Synthesis and investigation of the derivatives of amidinohydrazonelated aromatic compounds as furin inhibitors
The proprotein convertase furin plays a crucial role in a variety of pathogenic processes such as cancer, bacterial and viral diseases, neurodegenerative disorders and diabetes. Thus, furin inhibitors are promising therapeutics for the treatment of many diseases. In this study we synthesized some n...
Main Authors: | T. V. Osadchuk, A. V. Semyroz, O. V. Shybyryn, V. K. Kibirev |
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Format: | Article |
Language: | English |
Published: |
National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine.
2017-12-01
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Series: | Ukrainian Biochemical Journal |
Subjects: | |
Online Access: | http://ukrbiochemjournal.org/2017/12/synthesis-and-investigation-of-the-derivatives-of-amidinohydrazonelated-aromatic-compounds-as-furin-inhibitors.html |
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