A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders

The substantia nigra is important in neurological disease, particularly movement disorders. Here the authors provide a single cell transcriptomic atlas for the human substantia nigra.

Bibliographic Details
Main Authors:	Devika Agarwal, Cynthia Sandor, Viola Volpato, Tara M. Caffrey, Jimena Monzón-Sandoval, Rory Bowden, Javier Alegre-Abarrategui, Richard Wade-Martins, Caleb Webber
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-08-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-17876-0

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spelling	doaj-b479fe2c43c740f2a5200c552a91eb312021-08-22T11:41:45ZengNature Publishing GroupNature Communications2041-17232020-08-0111111110.1038/s41467-020-17876-0A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disordersDevika Agarwal0Cynthia Sandor1Viola Volpato2Tara M. Caffrey3Jimena Monzón-Sandoval4Rory Bowden5Javier Alegre-Abarrategui6Richard Wade-Martins7Caleb Webber8Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of OxfordUK Dementia Research Institute, Cardiff UniversityUK Dementia Research Institute, Cardiff UniversityOxford Parkinson’s Disease Centre, Department of Physiology, Anatomy, Genetics, University of OxfordUK Dementia Research Institute, Cardiff UniversityWellcome Trust Centre for Human GeneticsOxford Parkinson’s Disease Centre, Department of Physiology, Anatomy, Genetics, University of OxfordOxford Parkinson’s Disease Centre, Department of Physiology, Anatomy, Genetics, University of OxfordOxford Parkinson’s Disease Centre, Department of Physiology, Anatomy, Genetics, University of OxfordThe substantia nigra is important in neurological disease, particularly movement disorders. Here the authors provide a single cell transcriptomic atlas for the human substantia nigra.https://doi.org/10.1038/s41467-020-17876-0
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Devika Agarwal Cynthia Sandor Viola Volpato Tara M. Caffrey Jimena Monzón-Sandoval Rory Bowden Javier Alegre-Abarrategui Richard Wade-Martins Caleb Webber
spellingShingle	Devika Agarwal Cynthia Sandor Viola Volpato Tara M. Caffrey Jimena Monzón-Sandoval Rory Bowden Javier Alegre-Abarrategui Richard Wade-Martins Caleb Webber A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders Nature Communications
author_facet	Devika Agarwal Cynthia Sandor Viola Volpato Tara M. Caffrey Jimena Monzón-Sandoval Rory Bowden Javier Alegre-Abarrategui Richard Wade-Martins Caleb Webber
author_sort	Devika Agarwal
title	A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders
title_short	A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders
title_full	A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders
title_fullStr	A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders
title_full_unstemmed	A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders
title_sort	single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-08-01
description	The substantia nigra is important in neurological disease, particularly movement disorders. Here the authors provide a single cell transcriptomic atlas for the human substantia nigra.
url	https://doi.org/10.1038/s41467-020-17876-0
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A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders

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