Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination Survey
We aimed to estimate the cutoff value of glycated hemoglobin (HbA1c, A1c) for fasting plasma glucose (FPG) of 126 mg/dL in the Korean adult population, using the 2011 Korea National Health and Nutrition Examination Survey. A total of 5,421 participants without a history of diabetes and over 19 years...
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Korean Diabetes Association
2014-12-01
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Online Access: | http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-38-480.pdf |
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doaj-b483dbe9c8ec439684807ad70a4aec9d2020-11-25T00:24:45ZengKorean Diabetes AssociationDiabetes & Metabolism Journal2233-60792233-60872014-12-0138648048310.4093/dmj.2014.38.6.48014658Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination SurveyJung Min KimJae Won HongJong Chul WonJung Hyun NohKyung Soo KoByoung Doo RheeDong-Jun KimWe aimed to estimate the cutoff value of glycated hemoglobin (HbA1c, A1c) for fasting plasma glucose (FPG) of 126 mg/dL in the Korean adult population, using the 2011 Korea National Health and Nutrition Examination Survey. A total of 5,421 participants without a history of diabetes and over 19 years of age were included in the analysis. A point-wise area under the receiver operating characteristic curve was used to estimate the optimal A1c cutoff value. A1c threshold of 6.1% produced the highest sum of sensitivity (85.2%) and specificity (90.5%) for FPG of 126 mg/dL (area under the curve, 0.941, P<0.001). A1c of 6.5% produced a sensitivity of 67.7% and specificity of 98.0% for FPG of 126 mg/dL. Considering A1c as one of three criteria for the diagnosis of diabetes and the specificity of an A1c cutoff of 6.5%, the current diagnostic criteria of A1c≥6.5% might be acceptable in the Korean adult population.http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-38-480.pdfDiabetes mellitusDiagnosisHemoglobin A, glycated |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jung Min Kim Jae Won Hong Jong Chul Won Jung Hyun Noh Kyung Soo Ko Byoung Doo Rhee Dong-Jun Kim |
spellingShingle |
Jung Min Kim Jae Won Hong Jong Chul Won Jung Hyun Noh Kyung Soo Ko Byoung Doo Rhee Dong-Jun Kim Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination Survey Diabetes & Metabolism Journal Diabetes mellitus Diagnosis Hemoglobin A, glycated |
author_facet |
Jung Min Kim Jae Won Hong Jong Chul Won Jung Hyun Noh Kyung Soo Ko Byoung Doo Rhee Dong-Jun Kim |
author_sort |
Jung Min Kim |
title |
Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination Survey |
title_short |
Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination Survey |
title_full |
Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination Survey |
title_fullStr |
Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination Survey |
title_full_unstemmed |
Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination Survey |
title_sort |
glycated hemoglobin value for fasting plasma glucose of 126 mg/dl in korean: the 2011 korea national health and nutrition examination survey |
publisher |
Korean Diabetes Association |
series |
Diabetes & Metabolism Journal |
issn |
2233-6079 2233-6087 |
publishDate |
2014-12-01 |
description |
We aimed to estimate the cutoff value of glycated hemoglobin (HbA1c, A1c) for fasting plasma glucose (FPG) of 126 mg/dL in the Korean adult population, using the 2011 Korea National Health and Nutrition Examination Survey. A total of 5,421 participants without a history of diabetes and over 19 years of age were included in the analysis. A point-wise area under the receiver operating characteristic curve was used to estimate the optimal A1c cutoff value. A1c threshold of 6.1% produced the highest sum of sensitivity (85.2%) and specificity (90.5%) for FPG of 126 mg/dL (area under the curve, 0.941, P<0.001). A1c of 6.5% produced a sensitivity of 67.7% and specificity of 98.0% for FPG of 126 mg/dL. Considering A1c as one of three criteria for the diagnosis of diabetes and the specificity of an A1c cutoff of 6.5%, the current diagnostic criteria of A1c≥6.5% might be acceptable in the Korean adult population. |
topic |
Diabetes mellitus Diagnosis Hemoglobin A, glycated |
url |
http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-38-480.pdf |
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