Unaltered Liver Regeneration in Post-Cholestatic Rats Treated with the FXR Agonist Obeticholic Acid
In a previous study, obeticholic acid (OCA) increased liver growth before partial hepatectomy (PHx) in rats through the bile acid receptor farnesoid X-receptor (FXR). In that model, OCA was administered during obstructive cholestasis. However, patients normally undergo PHx several days after biliary...
Main Authors: | Lianne R. de Haan, Joanne Verheij, Rowan F. van Golen, Verena Horneffer-van der Horneffer-van der Sluis, Matthew R. Lewis, Ulrich H. W. Beuers, Thomas M. van Gulik, Steven W. M. Olde Damink, Frank G. Schaap, Michal Heger, Pim B. Olthof |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-02-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/11/2/260 |
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