Development of a Triple-Coaxial Flow Device for Fabricating a Hydrogel Microtube and Its Application to Bioremediation
This paper demonstrates a triple-coaxial flow device to continuously produce a hydrogel microtube using a microfluidic technique. The hydrogel microtube can encapsulate a microbial suspension, while allowing the diffusion of oxygen and nutrients into the microtube and preventing microbes from passin...
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doaj-b4a869d9990041bcb3ba05f1ef206d7e2020-11-24T23:12:24ZengMDPI AGMicromachines2072-666X2018-02-01927610.3390/mi9020076mi9020076Development of a Triple-Coaxial Flow Device for Fabricating a Hydrogel Microtube and Its Application to BioremediationKazuma Fujimoto0Kazuhiko Higashi1Hiroaki Onoe2Norihisa Miki3School of Integrated Design Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Kanagawa 223-8522, JapanSchool of Integrated Design Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Kanagawa 223-8522, JapanDepartment of Mechanical Engineering, Keio University, Yokohama 223-8522, JapanDepartment of Mechanical Engineering, Keio University, Yokohama 223-8522, JapanThis paper demonstrates a triple-coaxial flow device to continuously produce a hydrogel microtube using a microfluidic technique. The hydrogel microtube can encapsulate a microbial suspension, while allowing the diffusion of oxygen and nutrients into the microtube and preventing microbes from passing into or out of the microtube. The microtubes also enable the collection of the microbes after task completion without contaminating the environment. In our previous study, we used a double-coaxial flow device to produce the microtubes, but continuous production was a challenge. In the present study, we developed a microfluidic device that fabricates a triple-coaxial flow to enable continuous production of the microtubes. Here, we characterize the production capacity of the microtubes along with their properties and demonstrate bioremediation using microtubes encapsulating a microbial suspension.http://www.mdpi.com/2072-666X/9/2/76microtubestriple-coaxial flowmicrobesmicrofluidicsbioremediation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kazuma Fujimoto Kazuhiko Higashi Hiroaki Onoe Norihisa Miki |
spellingShingle |
Kazuma Fujimoto Kazuhiko Higashi Hiroaki Onoe Norihisa Miki Development of a Triple-Coaxial Flow Device for Fabricating a Hydrogel Microtube and Its Application to Bioremediation Micromachines microtubes triple-coaxial flow microbes microfluidics bioremediation |
author_facet |
Kazuma Fujimoto Kazuhiko Higashi Hiroaki Onoe Norihisa Miki |
author_sort |
Kazuma Fujimoto |
title |
Development of a Triple-Coaxial Flow Device for Fabricating a Hydrogel Microtube and Its Application to Bioremediation |
title_short |
Development of a Triple-Coaxial Flow Device for Fabricating a Hydrogel Microtube and Its Application to Bioremediation |
title_full |
Development of a Triple-Coaxial Flow Device for Fabricating a Hydrogel Microtube and Its Application to Bioremediation |
title_fullStr |
Development of a Triple-Coaxial Flow Device for Fabricating a Hydrogel Microtube and Its Application to Bioremediation |
title_full_unstemmed |
Development of a Triple-Coaxial Flow Device for Fabricating a Hydrogel Microtube and Its Application to Bioremediation |
title_sort |
development of a triple-coaxial flow device for fabricating a hydrogel microtube and its application to bioremediation |
publisher |
MDPI AG |
series |
Micromachines |
issn |
2072-666X |
publishDate |
2018-02-01 |
description |
This paper demonstrates a triple-coaxial flow device to continuously produce a hydrogel microtube using a microfluidic technique. The hydrogel microtube can encapsulate a microbial suspension, while allowing the diffusion of oxygen and nutrients into the microtube and preventing microbes from passing into or out of the microtube. The microtubes also enable the collection of the microbes after task completion without contaminating the environment. In our previous study, we used a double-coaxial flow device to produce the microtubes, but continuous production was a challenge. In the present study, we developed a microfluidic device that fabricates a triple-coaxial flow to enable continuous production of the microtubes. Here, we characterize the production capacity of the microtubes along with their properties and demonstrate bioremediation using microtubes encapsulating a microbial suspension. |
topic |
microtubes triple-coaxial flow microbes microfluidics bioremediation |
url |
http://www.mdpi.com/2072-666X/9/2/76 |
work_keys_str_mv |
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1725600854540550144 |