Opposing Effect of Naringenin and Quercetin on the Junctional Compartment of MDCK II Cells to Modulate the Tight Junction

Opposing Effect of Naringenin and Quercetin on the Junctional Compartment of MDCK II Cells to Modulate the Tight Junction

Maintaining tight junction (TJ) integrity is important for epithelial cell barriers. Previously, the enhancement of TJ integrity, induced by citrus-derived flavonoids, naringin (NRG) and hesperidin (HSD), was demonstrated, but the effects of their aglycones naringenin (NAR) and hesperetin (HST), and...

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Bibliographic Details
Main Authors: Mio Nakashima, Misaki Hisada, Natsuko Goda, Takeshi Tenno, Ayaka Kotake, Yuko Inotsume, Ikuo Kameoka, Hidekazu Hiroaki
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Nutrients
Subjects:
dynamic equilibrium of tight junction
flavonoids
epithelial barrier enhancer
5′ adenosine monophosphate (AMP)-activated protein kinase
phosphatidylinositol-3-phosphate kinase
tight junction integrity
Online Access:https://www.mdpi.com/2072-6643/12/11/3285

Internet

https://www.mdpi.com/2072-6643/12/11/3285

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