Prognostic Role of Survivin and Macrophage Infiltration Quantified on Protein and mRNA Level in Molecular Subtypes Determined by RT-qPCR of <i>KRT5</i>, <i>KRT20</i>, and <i>ERBB2</i> in Muscle-Invasive Bladder Cancer Treated by Adjuvant Chemotherapy

Prognostic Role of Survivin and Macrophage Infiltration Quantified on Protein and mRNA Level in Molecular Subtypes Determined by RT-qPCR of <i>KRT5</i>, <i>KRT20</i>, and <i>ERBB2</i> in Muscle-Invasive Bladder Cancer Treated by Adjuvant Chemotherapy

Objectives: Bladder cancer is a heterogeneous malignancy. Therefore, it is difficult to find single predictive markers. Moreover, most studies focus on either the immunohistochemical or molecular assessment of tumor tissues by next-generation sequencing (NGS) or PCR, while a combination of immunohis...

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Bibliographic Details
Main Authors: Thorsten H. Ecke, Adisch Kiani, Thorsten Schlomm, Frank Friedersdorff, Anja Rabien, Klaus Jung, Ergin Kilic, Peter Boström, Minna Tervahartiala, Pekka Taimen, Jan Gleichenhagen, Georg Johnen, Thomas Brüning, Stefan Koch, Jenny Roggisch, Ralph M. Wirtz
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
survivin
BIRC5
macrophage
KRT20
ERBB2
MIBC
Online Access:https://www.mdpi.com/1422-0067/21/19/7420

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