Vascularización renal fetal en preeclámpticas severas y embarazadas normotensas

• Main Authors: Eduardo Reyna Villasmil, Joel Santos Bolívar, Yolimar Navarro Briceño, Jorly Mejia Montilla, Nadia Reyna Villasmil, Andreina Fernández Ramírez, Marta Rondón Tapía
• Format: Article
• Language: English
• Published: Universidad de Los Andes 2016-12-01
• Series: Avances en Biomedicina
• Subjects: Vascularization; Renal; Preeclampsia; Fetus; Doppler
• Online Access: http://erevistas.saber.ula.ve/index.php/biomedicina/article/view/8074

The objective of research was to compare renal vascularization in fetus of severe preeclamptic patients with normotensive pregnant women. A case-control study was done at Hospital Central “Dr. Urquinaona”, Maracaibo, Venezuela, with 50 severe preeclamptic patients (grupo A) and 50 normotensive pregnant women (group B), all nulliparous and with gestational age over 30 weeks. Tridimensional and power Doppler evaluation was performed in each fetal kidney separately to calculate vascular indexes: vascularization index, flow index and vascularization – flow index. There were not found significant differences in maternal age and gestational age (p = ns). There were found significant differences in mean values of systolic and diastolic blood pressure and proteinuria between severe preeclamptic patients and normotensive pregnant women (p < 0.0001). Patients in group A presented significant lower values of vascularization index, flow index and vascularization – flow index compared with patients of group B (p < 0.0001). These differences were also evident for comparison between right and left kidney as mean combined measurement (p < 0.0001). Decrease of vascularization index, flow index and vascularization – flow index between severe preeclamptic patients and controls were above 30%, 34% and 54%, respectively. It is conclude that decreased of fetal renal vascularization could be measured and is significantly lower in severe preeclamptic patients compared with normotensive pregnant women