Bias estimation in study design: a meta-epidemiological analysis of transcatheter versus surgical aortic valve replacement

Abstract Background Paucity of RCTs of non-drug technologies lead to widespread dependence on non-randomized studies. Relationship between nonrandomized study design attributes and biased estimates of treatment effects are poorly understood. Our purpose was to estimate the bias associated with speci...

Full description

Bibliographic Details
Main Authors: Saerom Youn, Shannon Avery Wong, Caitlin Chrystoja, George Tomlinson, Harindra C. Wijeysundera, Chaim M. Bell, Anna R. Gagliardi, Nancy N. Baxter, Julie Takata, Lakhbir Sandhu, David Robert Urbach
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Surgery
Subjects:
Online Access:https://doi.org/10.1186/s12893-021-01278-0