Epidermal Wnt signalling regulates transcriptome heterogeneity and proliferative fate in neighbouring cells

Abstract Background Canonical Wnt/beta-catenin signalling regulates self-renewal and lineage selection within the mammalian epidermis. Although the transcriptional response of keratinocytes that receive a Wnt signal is well characterized, little is known about the mechanism by which keratinocytes in...

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Bibliographic Details
Main Authors: Arsham Ghahramani, Giacomo Donati, Nicholas M. Luscombe, Fiona M. Watt
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-017-1384-y

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