Epidermal Wnt signalling regulates transcriptome heterogeneity and proliferative fate in neighbouring cells
Abstract Background Canonical Wnt/beta-catenin signalling regulates self-renewal and lineage selection within the mammalian epidermis. Although the transcriptional response of keratinocytes that receive a Wnt signal is well characterized, little is known about the mechanism by which keratinocytes in...
Main Authors: | Arsham Ghahramani, Giacomo Donati, Nicholas M. Luscombe, Fiona M. Watt |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-01-01
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Series: | Genome Biology |
Online Access: | http://link.springer.com/article/10.1186/s13059-017-1384-y |
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