Fatal autonomic failure due to premanifesting Parkinson's disease only diagnosed at autopsy
Abstract A 46‐year‐old male had 11‐year history of cryptic autonomic dysfunction. He developed a fatal autonomic failure with diffuse hypoxic brain injury. Histology examination of medulla oblongata and the celiac ganglion revealed many α‐synuclein immunoreactive Lewy bodies confirming the diagnosis...
Main Authors: | Istvan Bodi, Ellen Merete Hagen, Gordon Thorpe Ingle, Michael P Lunn |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2020-10-01
|
Series: | Clinical Case Reports |
Subjects: | |
Online Access: | https://doi.org/10.1002/ccr3.3042 |
Similar Items
-
Pathological Functions of LRRK2 in Parkinson’s Disease
by: Ga Ram Jeong, et al.
Published: (2020-11-01) -
Direct and/or Indirect Roles for SUMO in Modulating Alpha-Synuclein Toxicity
by: Shamini Vijayakumaran, et al.
Published: (2015-07-01) -
Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies
by: P.G. Foulds, et al.
Published: (2012-01-01) -
Interactions between Calcium and Alpha-Synuclein in Neurodegeneration
by: Alex Rcom-H'cheo-Gauthier, et al.
Published: (2014-08-01) -
Beyond the synucleinopathies: alpha synuclein as a driving force in neurodegenerative comorbidities
by: Naomi P. Visanji, et al.
Published: (2019-09-01)