Evaluation of Ruthenium(II) <i>N</i>-Heterocyclic Carbene Complexes as Antibacterial Agents and Inhibitors of Bacterial Thioredoxin Reductase

Evaluation of Ruthenium(II) <i>N</i>-Heterocyclic Carbene Complexes as Antibacterial Agents and Inhibitors of Bacterial Thioredoxin Reductase

A series of ruthenium(II) complexes with <i>N</i>-heterocyclic carbene (NHC) ligands of the general type (arene)(NHC)Ru(II)X<sub>2</sub> (where X = halide) was prepared, characterized, and evaluated as antibacterial agents in comparison to the respective metal free benzimidaz...

Full description

Bibliographic Details
Main Authors:	Hilke Burmeister, Pascal Dietze, Lutz Preu, Julia E. Bandow, Ingo Ott
Format:	Article
Language:	English
Published:	MDPI AG 2021-07-01
Series:	Molecules
Subjects:	antibacterial <i>N</i>-heterocyclic carbenes ruthenium thioredoxin reductase
Online Access:	https://www.mdpi.com/1420-3049/26/14/4282

Similar Items

Synthesis and Reactivity of Poly(propyleneimine) Dendrimers Functionalized with Cyclopentadienone <i>N</i>-Heterocyclic-Carbene Ruthenium(0) Complexes
by: Cristiana Cesari, et al.
Published: (2020-02-01)

Specialized Olefin Metathesis Catalysts Featuring Unsymmetrical <i>N</i>-Heterocyclic Carbene Ligands Bearing <i>N</i>-(Fluoren-9-yl) Arm
by: Phillip I. Jolly, et al.
Published: (2020-05-01)

Ruthenium Olefin Metathesis Catalysts Featuring N-Heterocyclic Carbene Ligands Tagged with Isonicotinic and 4-(Dimethylamino)benzoic Acid Rests: Evaluation of a Modular Synthetic Strategy
by: Stefan Czarnocki, et al.
Published: (2021-08-01)

<i>N</i>-Heterocyclic Carbene Catalysis under Oxidizing Conditions
by: Krzysztof Dzieszkowski, et al.
Published: (2018-11-01)

Backbone tuning in indenylidene–ruthenium complexes bearing an unsaturated N-heterocyclic carbene
by: César A. Urbina-Blanco, et al.
Published: (2010-11-01)

Influence of Fluorine Substituents on the Electronic Properties of Selenium-<i>N</i>-Heterocyclic Carbene Compounds
by: Mohamad Shazwan Shah Jamil, et al.
Published: (2020-11-01)

Facile N9-Alkylation of Xanthine Derivatives and Their Use as Precursors for <i>N</i>-Heterocyclic Carbene Complexes
by: Moloud Mokfi, et al.
Published: (2021-06-01)

Design and Synthesis of Photoactive Iron <i>N</i>-Heterocyclic Carbene Complexes
by: Simon Kaufhold, et al.
Published: (2020-01-01)

Synthesis and Antimicrobial Properties of Silver(I) N-Heterocyclic Carbene Complexes
by: Melaiye, Abdulkareem M.
Published: (2005)

<i>N</i>-Heterocyclic Carbene Adducts of Alkynyl Functionalized 1,3,2-Dithioborolanes
by: Richard Böser, et al.
Published: (2019-04-01)

<i>N</i>-Heterocyclic Carbene-Polyethyleneimine (PEI) Platinum Complexes Inducing Human Cancer Cell Death: Polymer Carrier Impact
by: May Wantz, et al.
Published: (2018-11-01)

Recent Progress in <i>N</i>-Heterocyclic Carbene Gold-Catalyzed Reactions of Alkynes Involving Oxidation/Amination/Cycloaddition
by: Xiang-Ting Tang, et al.
Published: (2020-03-01)

The Combination of Lewis Acid with <i>N</i>-Heterocyclic Carbene (NHC) Catalysis
by: Qianfa Jia, et al.
Published: (2019-10-01)

A Ruthenium(II) <i>N</i>-Heterocyclic Carbene (NHC) Complex with Naphthalimide Ligand Triggers Apoptosis in Colorectal Cancer Cells via Activating the ROS-p38 MAPK Pathway
by: Yasamin Dabiri, et al.
Published: (2018-12-01)

Synthesis and structures of ruthenium–NHC complexes and their catalysis in hydrogen transfer reaction
by: Chao Chen, et al.
Published: (2015-09-01)

<i>N</i>-Heterocyclic Carbene Iron Complexes as Anticancer Agents: In Vitro and In Vivo Biological Studies
by: Oscar A. Lenis-Rojas, et al.
Published: (2021-09-01)

Ruthenium-Based Catalytic Systems Incorporating a Labile Cyclooctadiene Ligand with N-Heterocyclic Carbene Precursors for the Atom-Economic Alcohol Amidation Using Amines
by: Cheng Chen, et al.
Published: (2018-09-01)

Acenaphthene-Based <i>N</i>-Heterocyclic Carbene Metal Complexes: Synthesis and Application in Catalysis
by: Paulina Baczewska, et al.
Published: (2021-08-01)

Mercury(II) Complexes of Anionic <i>N</i>-Heterocyclic Carbene Ligands: Steric Effects of the Backbone Substituent
by: Chandrakanta Dash, et al.
Published: (2020-08-01)

Synthesis and Biological Studies on Dinuclear Gold(I) Complexes with Di-(<i>N</i>-Heterocyclic Carbene) Ligands Functionalized with Carbohydrates
by: Federica Tresin, et al.
Published: (2020-08-01)

Expression of Thioredoxin/Thioredoxin Reductase System Genes in Aphid-Challenged Maize Seedlings
by: Hubert Sytykiewicz, et al.
Published: (2020-08-01)

STUDIES OF THE COORDINATION CHEMISTRY AND CATALYTIC ACTIVITY OF RHODIUM AND RUTHENIUM N-HETEROCYCLIC CARBENE COMPLEXES
by: PRAETORIUS, Jeremy
Published: (2010)

Non-Classical Anionic Naked <i>N</i>-Heterocyclic Carbenes: Fundamental Properties and Emerging Applications in Synthesis and Catalysis
by: Mei Yi Leow, et al.
Published: (2018-12-01)

Olefin Metathesis with Ru-Based Catalysts Exchanging the Typical N-Heterocyclic Carbenes by a Phosphine–Phosphonium Ylide
by: Laia Arnedo, et al.
Published: (2017-03-01)

Enantiopure C1-symmetric N-Heterocyclic Carbene Ligands from Desymmetrized meso-1,2-Diphenylethylenediamine: Application in Ruthenium-Catalyzed Olefin Metathesis
by: Veronica Paradiso, et al.
Published: (2016-11-01)

Pd Nanocatalyst Adorned on Magnetic Chitosan@<i>N</i>-Heterocyclic Carbene: Eco-Compatible Suzuki Cross-Coupling Reaction
by: Roya Sedghi, et al.
Published: (2019-08-01)

Pyridine-Chelated Imidazo[1,5-<i>a</i>]Pyridine <i>N</i>-Heterocyclic Carbene Nickel(II) Complexes for Acrylate Synthesis from Ethylene and CO<sub>2</sub>
by: Jiyun Kim, et al.
Published: (2020-07-01)

Ruthenium complexes of new heterocyclic ligands.
by: Davison, Thomas William
Published: (2014)

Synthesis of Iron(II)–N-Heterocyclic Carbene Complexes: Paving the Way for a New Class of Antibiotics
by: Carolina S. Vinagreiro, et al.
Published: (2020-06-01)

The Natural Product Lepidiline A as an <i>N</i>-Heterocyclic Carbene Ligand Precursor in Complexes of the Type [Ir(cod)(NHC)PPh<sub>3</sub>)]X: Synthesis, Characterisation, and Application in Hydrogen Isotope Exchange Catalysis
by: Alison R. Cochrane, et al.
Published: (2020-02-01)

<i>N</i>-Heterocyclic Carbene Platinum(IV) as Metallodrug Candidates: Synthesis and <sup>195</sup>Pt NMR Chemical Shift Trend
by: Mathilde Bouché, et al.
Published: (2020-07-01)

Development of Cobalt and Nickel N-Heterocyclic Carbene Complexes for Cross-Coupling Reactions
by: Lazarus, Michael Evan
Published: (2020)

N-Heterocyclic Carbenes of the Late Transition Metals: A Computational and Structural Database Study
by: Baba, Eduard
Published: (2005)

Anti-cancer N-heterocyclic carbene complexes of gold(III), gold(I) and platinum(II) : thiol "switch-on" fluorescent probes, thioredoxin reductase inhibitors and endoplasmic reticulum targeting agents
by: Zou, Taotao, et al.
Published: (2015)

Design, Synthesis and Catalytic Activity of Di-<i>N</i>-Heterocyclic Carbene Complexes of Nickel and Palladium
by: Paulose, Tressia Alias Princy
Published: (2009)

A Stability Comparison and Antimicrobial Evaluation of Gold N-Heterocyclic Carbenes and Their Silver Precursors
by: Siciliano, Tammy J.
Published: (2008)

A DFT Study on the Redox Active Behavior of Carbene and Pyridine Ligands in the Oxidative and Reductive Quenching Cycles of Ruthenium Photoredox Catalysts
by: Edinson Medina, et al.
Published: (2020-01-01)

Novel N-heterocyclic carbene architectures for use in carbene based polymers and redox swithcable : catalysis
by: Kamplain, Justin Wade, 1980-
Published: (2012)

Ruthenium K-edge X-ray absorption spectroscopy studies of ruthenium complexes relevant to olefin metathesis
by: Getty, Kendra Joyce
Published: (2008)

Ruthenium K-edge X-ray absorption spectroscopy studies of ruthenium complexes relevant to olefin metathesis
by: Getty, Kendra Joyce
Published: (2008)