Agrin-Mediated Cardiac Regeneration: Some Open Questions
After cardiac injury, the mammalian adult heart has a very limited capacity to regenerate, due to the inability of fully differentiated cardiomyocytes (CMs) to efficiently proliferate. This has been directly linked to the extracellular matrix (ECM) surrounding and connecting cardiomyocytes, as its i...
Main Authors: | Maria Giulia Bigotti, Katie L. Skeffington, Ffion P. Jones, Massimo Caputo, Andrea Brancaccio |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-06-01
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Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fbioe.2020.00594/full |
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