Study of embryonic development and histological structure of the eye in white mouse Mus musculus

• Main Authors: Hani Hammodi, Raghed Abbas
• Format: Article
• Language: Arabic
• Published: College of Education for Pure Sciences 2007-09-01
• Series: مجلة التربية والعلم
• Subjects: embryonic development; mus musculus; optic nerve
• Online Access: https://edusj.mosuljournals.com/article_162950_73380ac05f77e40641371d7ce0d1b148.pdf

The present study aims to investigate the morphological,<br />anatomical and histological eye development of the swiss albino mice<br />mus musculus. The eye development initiated at early stage of pregnancy<br />and continued and represented for twelve stages, each stage per one day.<br />At full term delivery, the eye was closed and incomplete in<br />differentjation. The first signal of optic vesicle primordium appeared in<br />the first stage at th day of pregnancy and continued with enlargement in<br />the second stage. The optic vesicles was invaginated, at the 3 rd stage to<br />form the optic cup. At the same time, the lens primordium (Lens<br />placodes) appeared. In the 4th stage, the two layers of optic cup<br />differentiated and the lens disc involuted to form, The lens vesicle the<br />first retinal signal appeared at the 5th stage were ganglion cells. At the 6th<br />stage, several features appeared which include bruche 's· membrane,<br />choroid fissure, optic nerve primordium and spherical lens with lens fiber.<br />Then inner plexiform layer of the retina differentiated at the th stage. The<br />choroid and scleral tunics as well as the retinal nerve fiber layer appeared<br />at the gth stage. The cornea and iris primordia as well as the pigment<br />epithelial cells of the retina appeared at the 9th stage. At the 1oth stage the<br />optic nerve emerged from the ventral side of the eye ball. The distinct<br />features of the 11th stage were the appearance of the outer neural retina as<br />syncitiallayer with the differentiation of inner nerve fiber layers. On the<br />other hand, the eye chambers, and the differentiation of inner nuclear<br />retinal layer and the outer plexiform layer were developed at the last<br />stage.